Themed collection Journal of Materials Chemistry B Emerging Investigators
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Contributors to the Emerging Investigators 2021 issue
Journal of Materials Chemistry B profiles contributors to the Emerging Investigators 2021 issue.
J. Mater. Chem. B, 2021,9, 6932-6938
https://doi.org/10.1039/D1TB90133H
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RNA BioMolecular Electronics: towards new tools for biophysics and biomedicine
Nanoscience has enabled the electrical study of individual biomolecules. This perspective presents the nascent field of RNA BioMolecular Electronics, overviewing the main developments and exploring recent and future potential applications.
J. Mater. Chem. B, 2021,9, 6994-7006
https://doi.org/10.1039/D1TB01141C
Nanoparticle-mediated surfactant therapy in patients with severe COVID-19: a perspective
Nanoparticle-mediated surfactant therapy in patients with severe COVID-19.
J. Mater. Chem. B, 2021,9, 6988-6993
https://doi.org/10.1039/D1TB00730K
Multifunctional high-Z nanoradiosensitizers for multimodal synergistic cancer therapy
This review focuses on recent advances in multifunctional high-Z nanomaterials for radiotherapeutic-based multimodal synergistic cancer therapy.
J. Mater. Chem. B, 2022,10, 1328-1342
https://doi.org/10.1039/D1TB02524D
Electroactive nanomaterials in the peripheral nerve regeneration
Severe peripheral nerve injuries are threatening the life quality of human beings.
J. Mater. Chem. B, 2021,9, 6958-6972
https://doi.org/10.1039/D1TB00686J
Manganese oxide nanomaterials boost cancer immunotherapy
This review summarized the recent advances of manganese oxide nanomaterials for cancer immunotherapy, covering adjusting an immunosuppressive tumor microenvironment, inducing immunogenic cell death, immunoadjuvants for nanovaccines and so on.
J. Mater. Chem. B, 2021,9, 7117-7131
https://doi.org/10.1039/D1TB01001H
Smart near infrared-responsive nanocomposite hydrogels for therapeutics and diagnostics
This review article highlights recent research progress on the NIR-responsive nanocomposite hydrogels, focusing on their preparation, properties, applications and future prospectus.
J. Mater. Chem. B, 2021,9, 7100-7116
https://doi.org/10.1039/D1TB00980J
Superoxide dismutase nanozymes: an emerging star for anti-oxidation
This review summarizes catalytic mechanisms, regulatory factors, measurement methods and various applications of SOD-like nanozymes, as well as proposes the current challenges and prospects in the development of SOD-like nanozymes.
J. Mater. Chem. B, 2021,9, 6939-6957
https://doi.org/10.1039/D1TB00720C
Recent advances in the development of nitric oxide-releasing biomaterials and their application potentials in chronic wound healing
This paper reviews the recent progress in nitric oxide (NO) donors, biomaterial vectors, biomaterial-based NO delivery systems and NO synthetic enzyme mimics, and emphasizes the application potentials of NO releasing biomaterials in chronic wound healing.
J. Mater. Chem. B, 2021,9, 7063-7075
https://doi.org/10.1039/D1TB00847A
Recent near-infrared light-activated nanomedicine toward precision cancer therapy
This review summarizes the recent developments in different NIR-based nanomedicine for cancer therapy.
J. Mater. Chem. B, 2021,9, 7076-7099
https://doi.org/10.1039/D1TB00671A
Bringing naturally-occurring saturated fatty acids into biomedical research
This review introduces naturally-occurring saturated fatty acids (NSFAs) and their biomedical applications, including controlled drug release, targeted drug delivery, cancer therapy, antibacterial treatment, and tissue engineering.
J. Mater. Chem. B, 2021,9, 6973-6987
https://doi.org/10.1039/D1TB00843A
Biomacromolecule-based photo-thermal agents for tumor treatment
Recent advances in the design, fabrication, and applications of biomacromolecule-based photo-thermal agents are summarized. Cell membranes, proteins, nucleotides and polysaccharides are involved. Perspectives and challenges are also presented.
J. Mater. Chem. B, 2021,9, 7007-7022
https://doi.org/10.1039/D1TB00725D
DNA-based ribonuclease detection assays
This review describes some of the recent developments in DNA-based techniques for ribonuclease detection and discusses methodologies, assay metrics, screening of ribonuclease inhibitors, and future potential.
J. Mater. Chem. B, 2021,9, 7023-7029
https://doi.org/10.1039/D1TB00300C
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Polysaccharide nanoparticles: from fabrication to applications
The present review highlights the developments in polysaccharide nanoparticles with a particular focus on applications in biomedicine, cosmetics and food.
J. Mater. Chem. B, 2021,9, 7030-7062
https://doi.org/10.1039/D1TB00628B
Spatially heterogeneous epidermal growth factor release from microporous annealed particle (MAP) hydrogel for improved wound closure
We present lyophilized heparin microgels which can be directly rehydrated with epidermal growth factor and mixed with PEG microgels to form heterogenous MAP scaffolds. These EGF-releasing MAP scaffolds promote accelerated dermal wound healing.
J. Mater. Chem. B, 2021,9, 7132-7139
https://doi.org/10.1039/D1TB00715G
Kinetic control of chirality and circularly polarized luminescence in G-quartet materials
Here, we found that the handedness and CPL properties of G-quartet materials highly depends on its formation kinetics.
J. Mater. Chem. B, 2021,9, 7140-7144
https://doi.org/10.1039/D1TB00683E
pH-Sensitive branched β-glucan-modified liposomes for activation of antigen presenting cells and induction of antitumor immunity
pH-Sensitive branched β-glucan-modified liposomes promote antigen uptake and activation of dendritic cells in vitro, inducing anti-tumor immune responses in vivo.
J. Mater. Chem. B, 2021,9, 7713-7724
https://doi.org/10.1039/D1TB00786F
Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin
Vancomycin (Van) is an antibiotic of choice for many drug resistant infections but cannot be given orally due to its poor permeability. Encapsulation of Vancomycin within MSNs improved its gastrointestinal permeation and provided controlled release.
J. Mater. Chem. B, 2021,9, 7145-7166
https://doi.org/10.1039/D1TB01430G
Delivery of a system xc− inhibitor by a redox-responsive levodopa prodrug nanoassembly for combination ferrotherapy
A ferroptosis nano-prodrug (SSZ–Fe2+@DSSD) that can generate intercellular ROS and inhibit the system xc−-GSH-GPX4 pathway to enhance the cancer ferrotherapy.
J. Mater. Chem. B, 2021,9, 7172-7181
https://doi.org/10.1039/D1TB00742D
A ‘smart’ aptamer-functionalized continuous label-free cell catch–transport–release system
A ‘smart’ aptamer-functionalized catch–transport–release system was developed with facile fabrication for continuous, selective, high-throughput label-free cell sorting.
J. Mater. Chem. B, 2021,9, 7196-7204
https://doi.org/10.1039/D1TB00739D
Molecule-specific vibration-based chiral differentiation of Raman spectra using cysteine modified gold nanoparticles: the cases of tyrosine and phenylalanine
The chirality of amino acids plays a key role in many biochemical processes, with the development of spectroscopic analysis methods for the chiral differentiation of amino acids being significant.
J. Mater. Chem. B, 2021,9, 7167-7171
https://doi.org/10.1039/D1TB00983D
Hydrogel nanoparticle degradation influences the activation and survival of primary macrophages
The effect of nanoparticle (NP) internalization and subsequent degradation rate on cell lifespan has emerged as an important consideration for nanomedicine design, as macrophages and other phagocytes are primary clearance mechanisms of administered NP formulations.
J. Mater. Chem. B, 2021,9, 7246-7257
https://doi.org/10.1039/D1TB00982F
3D printed architected conducting polymer hydrogels
Rationally designed, 3D-printed architectures can effectively decouple the mechanical and electrical properties of conducting polymer hydrogels.
J. Mater. Chem. B, 2021,9, 7258-7270
https://doi.org/10.1039/D1TB00877C
Carambola-like Bi2Te3 superstructures with enhanced photoabsorption for highly efficient photothermal therapy in the second near-infrared biowindow
Carambola-like Bi2Te3 superstructures endow Bi2Te3@PEG with enhanced photoabsorption in the near-infrared region, making them a promising tool for highly efficient photothermal therapy in the second near-infrared biowindow.
J. Mater. Chem. B, 2021,9, 7271-7277
https://doi.org/10.1039/D1TB00694K
Synthesis-temperature-regulated multi-enzyme-mimicking activities of ceria nanozymes
Facile-regulation of the multi-enzyme-mimicking activities and effective guidelines from radar analysis established here advance the further biomedical applications of ceria-based nanozymes.
J. Mater. Chem. B, 2021,9, 7238-7245
https://doi.org/10.1039/D1TB00964H
Diatom-inspired 2D nitric oxide releasing anti-infective porous nanofrustules
This paper describes the development and antibacterial activity of a 2D nitric oxide releasing nanocomposite with a mesoporous structure inspired by nature's diatoms.
J. Mater. Chem. B, 2021,9, 7229-7237
https://doi.org/10.1039/D1TB00458A
Engineering Cu2−xS-conjugated upconverting nanocomposites for NIR-II light-induced enhanced chemodynamic/photothermal therapy of cancer
Cu2−xS-conjugated upconverting nanocomposites with an outstanding photothermal killing effect and a PT-enhanced CDT effect for NIR-II light-induced enhanced chemodynamic/photothermal therapy of cancer.
J. Mater. Chem. B, 2021,9, 7216-7228
https://doi.org/10.1039/D1TB00337B
Hyaluronic acid drives mesenchymal stromal cell-derived extracellular matrix assembly by promoting fibronectin fibrillogenesis
Hyaluronic acid (HA) is present at sites of ongoing fibronectin fibrillogenesis (fibrillar adhesions) and necessary for efficient fibronectin fibrillogenesis. As a result, fibronectin deposition can be enhanced by exogenous HA.
J. Mater. Chem. B, 2021,9, 7205-7215
https://doi.org/10.1039/D1TB00268F
Tannic acid-inspired, self-healing, and dual stimuli responsive dynamic hydrogel with potent antibacterial and anti-oxidative properties
Tannic acid cross-linked dynamic hydrogels hybridized with tannic acid reduced silver nanoparticles shows multi-functional properties including dual stimuli responsive drug release, anti-bacterial and anti-reactive oxygen species abilities.
J. Mater. Chem. B, 2021,9, 7182-7195
https://doi.org/10.1039/D1TB00156F
About this collection
Journal of Materials Chemistry B is proud to present this themed issue highlighting 2021’s rising stars of materials chemistry research. This issue gathers the very best work from materials chemists in the early stages of their independent career.
Each contributor was recommended by experts in their fields as carrying out work with the potential to influence future directions in materials chemistry with applications in biology and medicine. We would like to congratulate all the excellent researchers featured.