Designing antibacterial materials through simulation and theory
To broaden the application of antibacterial materials in nanomedicine, understanding the complex mechanisms and inherent properties is crucial. This review summarizes the advancements in computational and theoretical research in this emerging field.
Paper
Cell-specific spatial profiling of targeted protein expression to characterize the impact of intracortical microelectrode implantation on neuronal health
Multiplex immunochemistry for proteins examining neuronal structure or function in NeuN+ regions adjacent intracortical microelectrodes (MEA) more closely matched historic intracortical MEA recording performance than traditional IHC quantification.
Paper
Quantitative multiplexing of uric acid and creatinine using polydisperse plasmonic nanoparticles enabled by electrochemical-SERS and machine learning
Electrochemical SERS and machine learning are combined to enable quantitative multiplexed detection of uric acid (UA) and creatinine (CRN). Using polydisperse Ag nanoparticles, limits of detection of 0.13 μM and 0.35 μM for UA and CRN are achieved.
A chemiluminescence immunosensor for biomarker detection based on boronic acid-modified magnetic composite microspheres
A versatile and flexible immobilization technique based on the specific affinity interaction between boronic acid and cis-diol groups of antibodies for chemiluminescence immunoassay (CLIA) was developed for efficient biomarker detection.
Paper
Hydrophobicity as a tool for programming sequential mesophase transitions of enzyme-responsive polymeric amphiphiles
Tuning the hydrophobicity of di- and tri-block amphiphiles co-assembled into enzyme-responsive micelles controls the rate and timing of their mesophase transitions, essential for designing programmable polymeric systems with tailored functions.
Accelerated scarless wound healing by dynamical regulation of angiogenesis and inflammation with immobilized asiaticoside and magnesium ions in silk nanofiber hydrogels
Silk hydrogels containing asiaticoside and magnesium ions were used to tune the angiogenesis and inflammation dynamically. The hydrogels accelerated scarless wound healing, indicating synergistic reaction of asiaticoside and magnesium.
Quantitatively analyzing the dissociation and release of disulfide-containing organic nanoparticles
The disintegration and release of disulfide-containing organic nanoparticles were measured by using liquid chromatograph tandem mass spectrometry and fluorescence imaging, which accurately monitored the biological fate of nanoparticles.
Grafting and controlled release of antimicrobial peptides from mesoporous silica
Antimicrobial peptides are grafted onto mesoporous silica particles and films. Their controlled release is presented, using a green light-responsive linker, which enables tunable release-concentration-time profiles.
About this collection
This special collection marks 10 years of our Emerging Investigators, an annual collection launched in 2014 showcasing high quality research being carried out by international researchers in the early stages of their independent careers. In celebration of the 10th anniversary of this initiative, the collection features new exciting work from contributors to the early Emerging Investigator collections. We hope you enjoy discovering how their research has progressed over the last 10 years.
New articles will be added to this collection as they are published.