Themed collection Metallomics in China
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Metallomics in China
This editorial introduces the Metallomics in China themed issue, guest edited by Hongzhe Sun.
Metallomics, 2013,5, 782-783
https://doi.org/10.1039/C3MT90024J
Metallomics insights for in vivo studies of metal based nanomaterials
Rapid development of engineered nanomaterials (NMs) and growing biomedical applications necessitates new types of multifunctional NMs. Understanding behavior patterns of NMs in vivo and any potential health impacts are essential to ensure safety in the biomedical application of nanotechnologies.
Metallomics, 2013,5, 793-803
https://doi.org/10.1039/C3MT00093A
Association of arsenic with nutrient elements in rice plants
The interactions between As and macro-nutrients, as well as micro-nutrients in rice plants, is reviewed.
Metallomics, 2013,5, 784-792
https://doi.org/10.1039/C3MT20277A
Interaction of SlyD with HypB of Helicobacter pylori facilitates nickel trafficking
HpSlyD interacts with HpHypB through its insert-in-flap (IF) domain and delivers Ni2+ to HpHypB, which induces the dimerization of HpHypB and enhances its GTPase activity.
Metallomics, 2013,5, 804-807
https://doi.org/10.1039/C3MT00014A
Photophysical and cellular uptake properties of novel phosphorescent cyclometalated iridium(III) bipyridine D-fructose complexes
We report herein new phosphorescent iridium(III) fructose complexes; their inhibited uptake by unmodified fructose, mitochondria-localization behavior and photocytotoxic activity can be utilized in the development of new tumor-selective photodynamic therapeutics.
Metallomics, 2013,5, 808-812
https://doi.org/10.1039/C3MT20276C
Histidine-rich proteins in prokaryotes: metal homeostasis and environmental habitat-related occurrence
The occurrence of HRPs in the proteomes of prokaryotes is found to be related to their habitats.
Metallomics, 2013,5, 1423-1429
https://doi.org/10.1039/C3MT00059A
Binding of oxo-Cu2 clusters to ferric ion-binding protein A from Neisseria gonorrhoeae: a structural insight
A 2.1 Å resolution crystal revealed oxo-Cu2 clusters assembly in a metal-binding cleft of NgFbpA with two-tyrosine motif as ligands.
Metallomics, 2013,5, 1430-1439
https://doi.org/10.1039/C3MT00091E
Effects of metal ions and disulfide bonds on the activity of phosphodiesterase from Trimeresurus stejnegeri venom
TS-PDE has one class of Zn2+ binding site and two classes of Cu2+ binding site, including the high affinity activator sites and the low affinity sites. The phosphodiesterase activity of TS-PDE relies on its disulfide bonds and bimetallic cluster.
Metallomics, 2013,5, 920-927
https://doi.org/10.1039/C3MT00031A
Putative cobalt- and nickel-binding proteins and motifs in Streptococcus pneumoniae
Cobalt and nickel metalloproteome is involved in protein metabolism, carbonhydrate metabolism and gene expression regulation. Co- and Ni-binding motifs H(X)nH, M(X)nH and H(X)nM are identified.
Metallomics, 2013,5, 928-935
https://doi.org/10.1039/C3MT00126A
Structure-oriented bioinformatic approach exploring histidine-rich clusters in proteins
Spatially histidine-rich clusters (HrCs) are commonly found in proteins and their presence closely correlates with transition metal ions.
Metallomics, 2013,5, 904-912
https://doi.org/10.1039/C3MT00026E
Cellular response of E. coli upon Hg2+ exposure – a case study of advanced nuclear analytical approach to metalloproteomics
2-DE, when coupled with SRXRF, was used to identify proteins of interest in E. coli upon Hg exposure.
Metallomics, 2013,5, 913-919
https://doi.org/10.1039/C3MT20279H
The effects of EF-Ts and bismuth on EF-Tu in Helicobacter pylori: implications for an elegant timing for the introduction of EF-Ts in the elongation and EF-Tu as a potential drug target
The study suggests that elegant timing is essential for the introduction of EF-Ts into the elongation process and bismuth inhibits EF-Tu.
Metallomics, 2013,5, 888-895
https://doi.org/10.1039/C3MT20265H
Mercury modulates selenium activity via altering its accumulation and speciation in garlic (Allium sativum)
Hg can modulate Se activity via altering its distribution, accumulation and speciation in garlic which is grown under Se–Hg co-exposure conditions.
Metallomics, 2013,5, 896-903
https://doi.org/10.1039/C3MT20273A
Characterization of mercury-containing protein in human plasma
Mercury-containing protein was separated and characterized by 2D-HPLC-UV–ICP-MS.
Metallomics, 2013,5, 821-827
https://doi.org/10.1039/C3MT00036B
Selenoprotein P and selenoprotein M block Zn2+-mediated Aβ42 aggregation and toxicity
Due to their metal binding capacities, both SelP-H and SelM′ suppressed Zn2+-induced Aβ42 aggregation and thus exhibited antioxidant and neuroprotective functionalities.
Metallomics, 2013,5, 861-870
https://doi.org/10.1039/C3MT20282H
PtCl2(phen) disrupts the metal ions binding to amyloid-β peptide
PtCl2(phen) preferentially binds to the Cu2+/Zn2+ coordination site in Aβ and turns metal ions to the secondary coordination site.
Metallomics, 2013,5, 879-887
https://doi.org/10.1039/C3MT20262C
Effect of distal histidines on hydrogen peroxide activation by manganese reconstituted myoglobin
An acceleration effect on H2O2 activation by both His-43 and His-64 in an F43H MnIIIMb mutant was firstly demonstrated.
Metallomics, 2013,5, 828-835
https://doi.org/10.1039/C3MT20275E
Bis(acetylacetonato)-oxovanadium(IV), bis(maltolato)-oxovanadium(IV) and sodium metavanadate induce antilipolytic effects by regulating hormone -sensitive lipase and perilipin via activation of Akt
Possible mechanisms underlying vanadium compounds-induced antilipolytic effects in 3T3L1 adipocytes.
Metallomics, 2013,5, 813-820
https://doi.org/10.1039/C3MT00001J
Chemical interactions of mercury species and some transition and noble metals towards metallothionein (Zn7MT-2) evaluated using SEC /ICP-MS , RP-HPLC /ESI-MS and MALDI-TOF-MS
Chemical interactions of mercury species with Zn7MT-2 under physiological conditions were evaluated using mass and CD spectroscopies.
Metallomics, 2013,5, 855-860
https://doi.org/10.1039/C3MT00016H
Anticancer activity in human multiple myeloma U266 cells: synergy between cryptotanshinone and arsenic trioxide
Cytotoxicity of combined cryptotanshinone and arsenic trioxide treatment in multiple myeloma U266 cells.
Metallomics, 2013,5, 871-878
https://doi.org/10.1039/C3MT20272K
The induction of mitochondria-mediated apoptosis in cancer cells by ruthenium(II) asymmetric complexes
Four ruthenium(II) asymmetric complexes were found to possess potent cellular uptake properties and induce HeLa cell apoptosis by acting on mitochondrial pathways.
Metallomics, 2013,5, 844-854
https://doi.org/10.1039/C3MT20270D
Vanadium compounds modulate PPARγ activity primarily by increasing PPARγ protein levels in mouse insulinoma NIT-1 cells
Vanadium compounds increase PPARγ protein and modulate PPARγ phosphorylation in NIT-1 cells.
Metallomics, 2013,5, 836-843
https://doi.org/10.1039/C3MT20249F
About this collection
Highlighting the growth of the field of biometal science in China, this collection of articles from Metallomics aims to provide a showcase for some of the best researchers in this area. Guest Edited by Hongzhe Sun. New articles will be added to this collection as they are published.