An unprecedented copper-promoted radical-mediated alkenyl C(sp2)–H carbonylation of alkenes with polyhaloalkanes for divergently producing α,β-unsaturated esters and aldehydes is presented.
A photocatalyst-free, simple and green method for visible light driven photocatalytic synthesis of gem-dihaloenones from alkynes, tetrahalomethanes and water has been developed.
We present an approach involving Fe-catalyzed B–H and Si–H insertion of gem-dichloroalkanes. In contrast to previous strategies, our method uses gem-dihaloalkanes as non-stabilized carbene precursors and operates through a radical reaction pathway.
A titanium-catalyzed reductive cyclization of vinyl boronates with gem-dihaloalkanes is developed. α-Substituted cyclic boronates that are otherwise difficult to access, such as those with heteroatom-containing rings, are readily obtained.
The exhaustive HDH and DDH of CF3 groups in pyridines and the HDH of C(sp2)–X (X = F, Cl, Br, and I) bonds in pyridines and arenes were catalyzed by [Ni(COD)2] using NH3BH3 (for HDH) or ND3BD3 (for DDH) and KOtBu at room temperature.