A cascade-reaction enabled synergistic cancer starvation/ROS-mediated/chemo-therapy with an enzyme modified Fe-based MOF

Zongjun Liu, Tuo Li, Fang Han, You Wang, Yang Gan, Junhui Shi, Tianran Wang, Muhammad Luqman Akhtar and Yu Li

Biomater. Sci., 2019, 7, 3683
DOI: 10.1039/C9BM00641A

Dynamic light scattering and transmission electron microscopy in drug delivery: a roadmap for correct characterization of nanoparticles and interpretation of results

Sergey K. Filippov, Ramil Khusnutdinov, Anastasiia Murmiliuk, Wali Inam, Lucia Ya. Zakharova, Hongbo Zhang and Vitaliy V. Khutoryanskiy

Mater. Horiz., 2023, 10, 5354
DOI: 10.1039/D3MH00717K

Engineering of redox-triggered polymeric lipid hybrid nanocarriers for selective drug delivery to cancer cells

B. Siva Lokesh, Suresh Ajmeera, Rajat Choudhary, Sanjaya Kumar Moharana, C. S. Purohit and V. Badireenath Konkimalla

J. Mater. Chem. B, 2025, 13, 1437
DOI: 10.1039/D4TB01236D

Carrier-free nanodrugs with efficient drug delivery and release for cancer therapy: From intrinsic physicochemical properties to external modification

Heng Mei, Shengsheng Cai, Dennis Huang, Huile Gao, Jun Cao and Bin He

Bioactive Materials, 2022, 8, 220
DOI: 10.1016/j.bioactmat.2021.06.035

Recent advances in nanocarriers-based drug delivery for cancer therapeutics: A review

Pinky Yadav, Jigna Jain and Atul P. Sherje

Reactive and Functional Polymers, 2021, 165, 104970
DOI: 10.1016/j.reactfunctpolym.2021.104970

Harvesting stem cell exosomes from herringbone microfluidic bioreactor for wound healing

Junjie Huang, Hanxu Chen, Ning Li, Luoran Shang, Yan Bi and Yuanjin Zhao

Nano Today, 2023, 52, 101983
DOI: 10.1016/j.nantod.2023.101983

Self-assembled pH-responsive DNA nanosponges for targeted co-delivery of doxorubicin and capsaicin for colorectal cancer therapy

Charles Asakiya, Yangzi Zhang, Liye Zhu, Michael Ackah, Samad Tavakoli, Longjiao Zhu, Kunlun Huang and Wentao Xu

Biochemical Engineering Journal, 2023, 195, 108926
DOI: 10.1016/j.bej.2023.108926

Transformable Honeycomb‐Like Nanoassemblies of Carbon Dots for Regulated Multisite Delivery and Enhanced Antitumor Chemoimmunotherapy

Lin Hou, Dandan Chen, Ruiting Wang, Ruibing Wang, Huijuan Zhang, Zhenzhong Zhang, Zhihong Nie and Siyu Lu

Angew Chem Int Ed, 2021, 60, 6581
DOI: 10.1002/anie.202014397

Polymer-metal-organic framework hybrids for bioimaging and cancer therapy

Ding-Yi Fu, Xiao Liu, Xiaohua Zheng, Mengjiao Zhou, Weiqi Wang, Gaoxing Su, Tianqing Liu, Lei Wang and Zhigang Xie

Coordination Chemistry Reviews, 2022, 456, 214393
DOI: 10.1016/j.ccr.2021.214393

Synthesis and Evaluation of Novel Functional Polymers Derived from Renewable Jasmine Lactone for Stimuli‐Responsive Drug Delivery

Kuldeep Kumar Bansal, Ezgi Özliseli, Ari Rosling and Jessica Marianne Rosenholm

Adv Funct Materials, 2021, 31
DOI: 10.1002/adfm.202101998

Micromotors from Microfluidics

Yunru Yu, Jiahui Guo, Minhan Zou, Lijun Cai and Yuanjin Zhao

Chemistry An Asian Journal, 2019, 14, 2417
DOI: 10.1002/asia.201900290

PEGylated Redox/pH Dual‐Responsive Dendritic Prodrugs Based on Boltorn® H40 for Tumor Triggered Paclitaxel Delivery

Elham Mohammadi, Seyed Jamal Tabatabaei Rezaei, Keivan Nedaei, Ali Ramazani and Ali Ramazani

ChemistrySelect, 2023, 8
DOI: 10.1002/slct.202204246

Porous Hydrogel-Encapsulated Photonic Barcodes for Multiplex Detection of Cardiovascular Biomarkers

JingJing Ji, Wenbin Lu, Yi Zhu, Hong Jin, Yuyu Yao, Huidan Zhang and Yuanjin Zhao

ACS Sens., 2019, 4, 1384
DOI: 10.1021/acssensors.9b00352

Helper T Cell (CD4+) Targeted Tacrolimus Delivery Mediates Precise Suppression of Allogeneic Humoral Immunity

Jia Shen, Chang Liu, Pengpeng Yan, Meifang Wang, Luying Guo, Shuaihui Liu, Jianghua Chen, Jessica M. Rosenholm, Hongfeng Huang, Rending Wang and Hongbo Zhang

Research, 2022, 2022
DOI: 10.34133/2022/9794235

Microfluidic spinning of natural origin microfibers for breast tumor postsurgical treatment

Yi Chen, Jiahui Guo, Xiangyi Wu, Ye Xu, Jinglin Wang, Haozhen Ren and Yuanjin Zhao

Chemical Engineering Journal, 2023, 472, 144901
DOI: 10.1016/j.cej.2023.144901

Activable Nano‐Immunomodulator Assembled from π‐Extended Naphthalenediimide for Precision Photothermal Immunotherapy

Wenbin Zhong, Wei Yuan, Yun Chen, Zhaoyu Ma, Mengmeng Ma, Brynne Shu Ni Tan, Jie Yang and Yanli Zhao

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202401250

Microfluidic assembly of small-molecule prodrug cocktail nanoparticles with high reproducibility for synergistic combination of cancer therapy

Tingting Li, Jiangling Huang, Min Wang and Hangxiang Wang

International Journal of Pharmaceutics, 2021, 608, 121088
DOI: 10.1016/j.ijpharm.2021.121088

Strategic chemical synthesis and application of nanocarriers responsive to the tumor microenvironment

Qinjiao Pang, Zhe Xu, Ting Sun, Shengqing Yue, Yue Yu, Haiying Lu, Mingfang He, Xingyu Chen, Yongping Lu and Jianshu Li

Nano Today, 2024, 58, 102421
DOI: 10.1016/j.nantod.2024.102421

Taxanes prodrug-based nanomedicines for cancer therapy

Linlin Sun, Pan Zhao, Menghan Chen, Jiayi Leng, Yixin Luan, Baoxiang Du, Jia Yang, Yong Yang and Rong Rong

Journal of Controlled Release, 2022, 348, 672
DOI: 10.1016/j.jconrel.2022.06.004

Combination of photothermal, prodrug and tumor cell camouflage technologies for triple-negative breast cancer treatment

Lirong Zhang, Xiaodong Ma, Wenhui Zhou, Qiwei Wu, Jiaqi Yan, Xiaoyu Xu, Bhawana Ghimire, Jessica M. Rosenholm, Jing Feng, Dongqing Wang and Hongbo Zhang

Materials Today Advances, 2022, 13, 100199
DOI: 10.1016/j.mtadv.2021.100199

Low Molecular Weight Modifications of Anthracycline Antibiotics. Part I. Reactions by Amino Group (A Review)

A. V. Semakov

rev. and adv. in chem., 2024, 14, 345
DOI: 10.1134/S2634827624600440

Responsive Janus Structural Color Hydrogel Micromotors for Label-Free Multiplex Assays

Huan Wang, Lijun Cai, Dagan Zhang, Luoran Shang and Yuanjin Zhao

Research, 2021, 2021
DOI: 10.34133/2021/9829068

Polymer-based and stimulus-responsive carriers for controlled release of agrochemicals

Ling Zheng, Farzad Seidi, Yuqian Liu, Weibing Wu and Huining Xiao

European Polymer Journal, 2022, 177, 111432
DOI: 10.1016/j.eurpolymj.2022.111432

Immunotherapeutic silk inverse opal particles for post-surgical tumor treatment

Hui Zhang, Yuxiao Liu, Guopu Chen, Huan Wang, Canwen Chen, Minli Li, Peihua Lu and Yuanjin Zhao

Science Bulletin, 2020, 65, 380
DOI: 10.1016/j.scib.2019.10.023

Self-Assembled Disulfide Bond Bearing Paclitaxel—Camptothecin Prodrug Nanoparticle for Lung Cancer Therapy

Jingyan Gao, Xiaodong Ma, Lirong Zhang, Jiaqi Yan, Huaguang Cui, Yuezhou Zhang, Dongqing Wang and Hongbo Zhang

Pharmaceutics, 2020, 12, 1169
DOI: 10.3390/pharmaceutics12121169

Magnetic Hydrogel Microrobots Delivery System for Deafness Prevention

Hong Chen, Hui Zhang, Yanhong Dai, Haofang Zhu, Guodong Hong, Chengwen Zhu, Xiaoyun Qian, Renjie Chai, Xia Gao and Yuanjin Zhao

Adv Funct Materials, 2023, 33
DOI: 10.1002/adfm.202303011

Nano Differential Scanning Fluorimetry as a Rapid Stability Assessment Tool in the Nanoformulation of Proteins

Sofia Lisina, Wali Inam, Mikko Huhtala, Fadak Howaili, Hongbo Zhang and Jessica M. Rosenholm

Pharmaceutics, 2023, 15, 1473
DOI: 10.3390/pharmaceutics15051473

Continuous Preparation of Semiconducting Polymer Nanoparticles with Varied Sizes for Online Fluorescence Sensing via a Laser-Tailored 3D Microfluidic Chip

Ruixuan Hu, Xiaolong Li, Jian Xu, Ya Cheng, Min Zhang and Guoyue Shi

Anal. Chem., 2023, 95, 10422
DOI: 10.1021/acs.analchem.3c01779

Internal stimuli-responsive Nanocarriers for Controlled anti-cancer Drug Release: a Review

Baji Baba Shaik, Naresh Kumar Katari and Sreekanth B Jonnalagadda

Ther. Deliv., 2023, 14, 595
DOI: 10.4155/tde-2023-0041

Solid-phase interfacial synthesis of dual-imprinted colloid particles for multifunctional nanomedicine development

Yin Cui, Ming Li, Xia Hong, Daolin Du and Yue Ma

Colloid and Interface Science Communications, 2020, 36, 100267
DOI: 10.1016/j.colcom.2020.100267

Quantum dots from microfluidics for nanomedical application

Feika Bian, Lingyu Sun, Lijun Cai, Yu Wang and Yuanjin Zhao

WIREs Nanomed Nanobiotechnol, 2019, 11
DOI: 10.1002/wnan.1567

Functionalized Block Co‐Polymer Pro‐Drug Nanoparticles with Anti‐Cancer Efficacy in 3D Spheroids and in an Orthotopic Triple Negative Breast Cancer Model

Vincenzo Taresco, Thais F. Abelha, Robert J. Cavanagh, Catherine E. Vasey, Akosua B. Anane‐Adjei, Amanda K. Pearce, Patrícia F. Monteiro, Keith A. Spriggs, Philip Clarke, Alison Ritchie, Stewart Martin, Ruman Rahman, Anna M. Grabowska, Marianne B. Ashford and Cameron Alexander

Advanced Therapeutics, 2021, 4
DOI: 10.1002/adtp.202000103

Redox-sensitive nanoscale drug delivery systems for cancer treatment

Elaheh Mirhadi, Mohammad Mashreghi, Mahdi Faal Maleki, Seyedeh Hoda Alavizadeh, Leila Arabi, Ali Badiee and Mahmoud Reza Jaafari

International Journal of Pharmaceutics, 2020, 589, 119882
DOI: 10.1016/j.ijpharm.2020.119882

Bioinspired structural color particles with multi-layer graphene oxide encapsulated nanoparticle components

Yuxiao Liu, Yuetong Wang, Yu Wang, Yilai Shu, Hui Tan and Yuanjin Zhao

Bioactive Materials, 2020, 5, 917
DOI: 10.1016/j.bioactmat.2020.06.013

Precision biomaterials in cancer theranostics and modelling

David Caballero, Catarina M. Abreu, Ana C. Lima, Nuno M. Neves, Rui L. Reis and Subhas C. Kundu

Biomaterials, 2022, 280, 121299
DOI: 10.1016/j.biomaterials.2021.121299

Bio-inspired intestinal scavenger from microfluidic electrospray for detoxifying lipopolysaccharide

Cheng Zhao, Guopu Chen, Huan Wang, Yuanjin Zhao and Renjie Chai

Bioactive Materials, 2021, 6, 1653
DOI: 10.1016/j.bioactmat.2020.11.017

Mutual boost between free radicals and photothermal effect for synergistic photothermal/thermodynamic antibacterial therapy

Haimeng Liu, Chengyang Ban, Chen Fang, Ru Xia, Jiasheng Qian, Jibin Miao and Ming Cao

Colloids and Surfaces B: Biointerfaces, 2025, 253, 114742
DOI: 10.1016/j.colsurfb.2025.114742

Engineering small molecule nanodrugs to overcome barriers for cancer therapy

Yuan Ma, Quanbing Mou, Deyue Yan and Xinyuan Zhu

VIEW, 2020, 1
DOI: 10.1002/VIW.20200062

Porphyrin Centered Paclitaxel Tetrameric Prodrug Nanoassemblies as Tumor‐Selective Theranostics for Synergized Breast Cancer Therapy

Xiaodong Ma, Pengfei Wang, Qiwei Wu, Junnian Zhou, Dongqing Wang, Deependra Yadav, Hongbo Zhang and Yuezhou Zhang

Adv Healthcare Materials, 2023, 12
DOI: 10.1002/adhm.202202024

Conductive Materials with Elaborate Micro/Nanostructures for Bioelectronics

Jiahui Guo, Yu Wang, Hui Zhang and Yuanjin Zhao

Advanced Materials, 2022, 34
DOI: 10.1002/adma.202110024

Conducting Polymeric Nanocomposites with a Three-Dimensional Co-flow Microfluidics Platform

Xiaodong Ma, Yuezhou Zhang and Korbinian Weisensee

Micromachines, 2019, 10, 383
DOI: 10.3390/mi10060383

Multiple Bio‐Actives Loaded Gellan Gum Microfibers from Microfluidics for Wound Healing

Jiahui Guo, Yunru Yu, Yingbo Shen, Xiaoyan Sun, Yan Bi and Yuanjin Zhao

Small, 2023, 19
DOI: 10.1002/smll.202303887

Nanoparticulation of Prodrug into Medicines for Cancer Therapy

Yuezhou Zhang, Huaguang Cui, Ruiqi Zhang, Hongbo Zhang and Wei Huang

Advanced Science, 2021, 8
DOI: 10.1002/advs.202101454

Recent trends in bioresponsive linker technologies of Prodrug-Based Self-Assembling nanomaterials

Anne Nguyen, Roland Böttger and Shyh-Dar Li

Biomaterials, 2021, 275, 120955
DOI: 10.1016/j.biomaterials.2021.120955

pH and GSH dual-responsive fluorescent nanoparticles from polydopamine coating mesoporous silica for controlled drug release and real-time detection

Hengquan Zhou, Guiying Li, Lei Guo, Qian Tao, Songmei Ma and Xunyong Liu

International Journal of Polymeric Materials and Polymeric Biomaterials, 2022, 71, 1131
DOI: 10.1080/00914037.2021.1951725

Overview of Nanoparticle-Based Approaches for the Combination of Photodynamic Therapy (PDT) and Chemotherapy at the Preclinical Stage

Luca Menilli, Celeste Milani, Elena Reddi and Francesca Moret

Cancers, 2022, 14, 4462
DOI: 10.3390/cancers14184462

Construction of reduction-sensitive heterodimer prodrugs of doxorubicin and dihydroartemisinin self-assembled nanoparticles with antitumor activity

Guolian Ren, Danyu Duan, Geng Wang, Rongrong Wang, Yujie Li, Hengtong Zuo, Qichao Zhang, Guoshun Zhang, Yongdan Zhao, Ruili Wang and Shuqiu Zhang

Colloids and Surfaces B: Biointerfaces, 2022, 217, 112614
DOI: 10.1016/j.colsurfb.2022.112614

Effective Delivery of the CRISPR/Cas9 System Enabled by Functionalized Mesoporous Silica Nanoparticles for GFP‐Tagged Paxillin Knock‐In

Xiaoyu Xu, Oliver Koivisto, Chang Liu, Junnian Zhou, Mitro Miihkinen, Guillaume Jacquemet, Daqi Wang, Jessica M. Rosenholm, Yilai Shu and Hongbo Zhang

Advanced Therapeutics, 2021, 4
DOI: 10.1002/adtp.202000072

Redox-responsive tumor targeted dual-drug loaded biocompatible metal–organic frameworks nanoparticles for enhancing anticancer effects

Chang Liu, Xiaoyu Xu, Junnian Zhou, Jiaqi Yan, Dongqing Wang and Hongbo Zhang

BMC Mat, 2020, 2
DOI: 10.1186/s42833-020-00013-y

Folic Acid-Modified Erythrocyte Membrane Loading Dual Drug for Targeted and Chemo-Photothermal Synergistic Cancer Therapy

Zhihao Chen, Wanting Wang, Yusheng Li, Cui Wei, Ping Zhong, Dahua He, Huan Liu, Pengfei Wang, Zhenpeng Huang, Wanye Zhu, Yi Zhou and Linghao Qin

Mol. Pharmaceutics, 2021, 18, 386
DOI: 10.1021/acs.molpharmaceut.0c01008

Dimeric prodrug-based nanomedicines for cancer therapy

Shumeng Li, Xinzhu Shan, Yuequan Wang, Qin Chen, Jin Sun, Zhonggui He, Bingjun Sun and Cong Luo

Journal of Controlled Release, 2020, 326, 510
DOI: 10.1016/j.jconrel.2020.07.036

Activable Nano‐Immunomodulator Assembled from π‐Extended Naphthalenediimide for Precision Photothermal Immunotherapy

Wenbin Zhong, Wei Yuan, Yun Chen, Zhaoyu Ma, Mengmeng Ma, Brynne Shu Ni Tan, Jie Yang and Yanli Zhao

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202401250

Synergy of Microfluidics and Nanomaterials: A Revolutionary Approach for Cancer Management

Pramoda G, Mansi Singh, Piyush Kumar Gupta and Rahul Shukla

ACS Appl. Bio Mater., 2025, 8, 2716
DOI: 10.1021/acsabm.5c00123

Transformable Honeycomb‐Like Nanoassemblies of Carbon Dots for Regulated Multisite Delivery and Enhanced Antitumor Chemoimmunotherapy

Lin Hou, Dandan Chen, Ruiting Wang, Ruibing Wang, Huijuan Zhang, Zhenzhong Zhang, Zhihong Nie and Siyu Lu

Angewandte Chemie, 2021, 133, 6655
DOI: 10.1002/ange.202014397

Fabrication of a pH/Redox-Triggered Mesoporous Silica-Based Nanoparticle with Microfluidics for Anticancer Drugs Doxorubicin and Paclitaxel Codelivery

Jiaqi Yan, Xiaoyu Xu, Junnian Zhou, Chang Liu, Lirong Zhang, Dongqing Wang, Fan Yang and Hongbo Zhang

ACS Appl. Bio Mater., 2020, 3, 1216
DOI: 10.1021/acsabm.9b01111

Self-assembly of oxidation-responsive polyethylene glycol-paclitaxel prodrug for cancer chemotherapy

Chengyuan Dong, Quan Zhou, Jiajia Xiang, Fusheng Liu, Zhuxian Zhou and Youqing Shen

Journal of Controlled Release, 2020, 321, 529
DOI: 10.1016/j.jconrel.2020.02.038