Possible chemical and physical scenarios towards biological homochirality

Quentin Sallembien, Laurent Bouteiller, Jeanne Crassous and Matthieu Raynal

Chem. Soc. Rev., 2022, 51, 3436
DOI: 10.1039/D1CS01179K

Strategies for chiral separation: from racemate to enantiomer

Jingchen Sui, Na Wang, Jingkang Wang, Xin Huang, Ting Wang, Lina Zhou and Hongxun Hao

Chem. Sci., 2023, 14, 11955
DOI: 10.1039/D3SC01630G

Rapid deracemization through solvent cycling: proof-of-concept using a racemizable conglomerate clopidogrel precursor

Sjoerd W. van Dongen, Iaroslav Baglai, Michel Leeman, Richard M. Kellogg, Bernard Kaptein and Willem L. Noorduin

Chem. Commun., 2023, 59, 3838
DOI: 10.1039/D3CC00332A

Particle Breakage Kinetics and Mechanisms in Attrition-Enhanced Deracemization

Christos Xiouras, Antonios A. Fytopoulos, Joop H. Ter Horst, Andreas G. Boudouvis, Tom Van Gerven and Georgios D. Stefanidis

Crystal Growth & Design, 2018, 18, 3051
DOI: 10.1021/acs.cgd.8b00201

Crystal‐Packing‐Driven Enrichment of Atropoisomers

Mona Sharafi, Joseph P. Campbell, Sinu C. Rajappan, Natavan Dudkina, Danielle L. Gray, Toby J. Woods, Jianing Li and Severin T. Schneebeli

Angewandte Chemie, 2017, 129, 7203
DOI: 10.1002/ange.201701876

Spontaneous Deracemizations

Thomas Buhse, José-Manuel Cruz, María E. Noble-Terán, David Hochberg, Josep M. Ribó, Joaquim Crusats and Jean-Claude Micheau

Chem. Rev., 2021, 121, 2147
DOI: 10.1021/acs.chemrev.0c00819

Design, Development, and Analysis of an Automated Sampling Loop for Online Monitoring of Chiral Crystallization

Ghufran ur Rehman, Thomas Vetter and Philip A. Martin

Org. Process Res. Dev., 2022, 26, 1063
DOI: 10.1021/acs.oprd.1c00320

Mechanism of chirality conversion of crystals by Viedma ripening and temperature cycling

Makio Uwaha and Hiroyasu Katsuno

Journal of Crystal Growth, 2022, 598, 126873
DOI: 10.1016/j.jcrysgro.2022.126873

Deracemization of a Racemic Compound by Using Tailor‐Made Additives

Anthonius H. J. Engwerda, Pim van Schayik, Henjo Jagtenberg, Hugo Meekes, Floris P. J. T. Rutjes and Elias Vlieg

Chemistry A European J, 2018, 24, 2863
DOI: 10.1002/chem.201706088

Anomalous Size Distribution of Chiral Crystals during Deracemization by Grinding

Hiroyasu Katsuno and Makio Uwaha

Crystal Growth & Design, 2019, 19, 2428
DOI: 10.1021/acs.cgd.9b00095

Deracemization of a Racemic Allylic Sulfoxide Using Viedma Ripening

Anthonius H. J. Engwerda, Niels Koning, Paul Tinnemans, Hugo Meekes, F. Matthias Bickelhaupt, Floris P. J. T. Rutjes and Elias Vlieg

Crystal Growth & Design, 2017, 17, 4454
DOI: 10.1021/acs.cgd.7b00828

Enantiopurity by Directed Evolution of Crystal Stabilities and Nonequilibrium Crystallization

Clément Pinetre, Sjoerd W. van Dongen, Clément Brandel, Anne-Sophie Léonard, Maxime D. Charpentier, Valérie Dupray, Kasper Oosterling, Bernard Kaptein, Michel Leeman, Richard M. Kellogg, Joop H. ter Horst and Willem L. Noorduin

J. Am. Chem. Soc., 2025, 147, 8864
DOI: 10.1021/jacs.5c00569

A Novel Strategy for Deracemization Using Periodic Fluctuations of Concentration

Kritsada Intaraboonrod and Adrian E. Flood

Chem Eng & Technol, 2023, 46, 2310
DOI: 10.1002/ceat.202200624

Resolution of a Metastable Racemic Compound of Anhydrous Phencyphos by Hydrate Formation

Michel Leeman and Richard M. Kellogg

Crystals, 2021, 11, 1225
DOI: 10.3390/cryst11101225

Crystallisation Based Deracemisation and Chiral Resolution of Small Molecules

Abhay S. K. Saseendran, Haritha Jayaraj, Krishnan Kartha Kalathil and Anjana Suseelan Sarala

Chemistry An Asian Journal, 2025
DOI: 10.1002/asia.202401465

Crystal‐Packing‐Driven Enrichment of Atropoisomers

Mona Sharafi, Joseph P. Campbell, Sinu C. Rajappan, Natavan Dudkina, Danielle L. Gray, Toby J. Woods, Jianing Li and Severin T. Schneebeli

Angew Chem Int Ed, 2017, 56, 7097
DOI: 10.1002/anie.201701876

Designing single chirality via crystallization method: spontaneous chiral symmetry breaking and deracemization

Bowen Zhang, Xiaotong Sun and Peng Du

Materials Today Chemistry, 2023, 32, 101636
DOI: 10.1016/j.mtchem.2023.101636

Toward Continuous Deracemization via Racemic Crystal Transformation Monitored by in Situ Raman Spectroscopy

Christos Xiouras, Giuseppe Belletti, Raghunath Venkatramanan, Alison Nordon, Hugo Meekes, Elias Vlieg, Georgios D. Stefanidis and Joop H. Ter Horst

Crystal Growth & Design, 2019, 19, 5858
DOI: 10.1021/acs.cgd.9b00867

Isothermal Deracemization of Sodium Chlorate in an Agitated Reactor: The Effect of Crystal Size Variables

Bowen Zhang, Gerard Coquerel and Woo-Sik Kim

Crystal Growth & Design, 2023, 23, 741
DOI: 10.1021/acs.cgd.2c00871

Photoracemization‐Based Viedma Ripening of a BINOL Derivative

Giuseppe Belletti, Carola Tortora, Indradevi D. Mellema, Paul Tinnemans, Hugo Meekes, Floris P. J. T. Rutjes, Svetlana B. Tsogoeva and Elias Vlieg

Chemistry A European J, 2020, 26, 839
DOI: 10.1002/chem.201904382