Towards medicinal mechanochemistry: evolution of milling from pharmaceutical solid form screening to the synthesis of active pharmaceutical ingredients (APIs)

Davin Tan, Leigh Loots and Tomislav Friščić

Chem. Commun., 2016, 52, 7760
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Controllable assembly of Cu(ii) coordination compounds based on a flexible zwitterionic benzimidazole–dicarboxylate ligand: synthesis, structural diversity, reversible SCSC transformation and magnetic properties

Yan-Fang Feng, Qi Tang, Kai-Liang Luo, Ji-Qing Wu, Zhong Zhang, Yu-Ning Liang and Fu-Pei Liang

CrystEngComm, 2017, 19, 5442
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A turn-on fluorescence sensor for cyanide from mechanochemical reactions between quantum dots and copper complexes

Carmen R. Maldonado, Angeles Touceda-Varela, Anita C. Jones and Juan C. Mareque-Rivas

Chem. Commun., 2011, 47, 11700
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A model for a solvent-free synthetic organic research laboratory: click-mechanosynthesis and structural characterization of thioureas without bulk solvents

Vjekoslav Štrukil, Marina D. Igrc, László Fábián, Mirjana Eckert-Maksić, Scott L. Childs, David G. Reid, Melinda J. Duer, Ivan Halasz, Cristina Mottillo and Tomislav Friščić

Green Chem., 2012, 14, 2462
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Polymorphic gabapentin: thermal behaviour, reactivity and interconversion of forms in solution and solid-state

Dario Braga, Fabrizia Grepioni, Lucia Maini, Katia Rubini, Marco Polito, Roberto Brescello, Livius Cotarca, M. Teresa Duarte, Vânia André and M. Fátima M. Piedade

New J. Chem., 2008, 32, 1788
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Drug-containing coordination and hydrogen bonding networks obtained mechanochemically

Dario Braga, Fabrizia Grepioni, Vânia André and M. Teresa Duarte

CrystEngComm, 2009, 11, 2618
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Towards an environmentally-friendly laboratory: dimensionality and reactivity in the mechanosynthesis of metal–organic compounds

Vjekoslav Štrukil, László Fábián, David G. Reid, Melinda J. Duer, Graham J. Jackson, Mirjana Eckert-Maksić and Tomislav Friščić

Chem. Commun., 2010, 46, 9191
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Tailoring the structures and transformations between copper complexes in gas–solid reactions and solid-state synthesis

Haitao Li, Ruhui Li and Fang Guo

Inorg. Chem. Front., 2020, 7, 4452
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Mechanochemical and silica gel-mediated formation of highly electron-poor 1-cyanocarbonylferrocene

Daniel Nieto, Sonia Bruña, M. Merced Montero-Campillo, Josefina Perles, Ana Ma González-Vadillo, Julia Méndez, Otilia Mo and Isabel Cuadrado

Chem. Commun., 2013, 49, 9785
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Mechanochemistry of magnesium oxide revisited: facile derivatisation of pharmaceuticals using coordination and supramolecular chemistry

Ernest H. H. Chow, Fiona C. Strobridge and Tomislav Friščić

Chem. Commun., 2010, 46, 6368
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Searching for novel crystal forms by in situ high-pressure crystallisation: the example of gabapentin heptahydrate

Francesca P. A. Fabbiani, Demetrius C. Levendis, Gernot Buth, Werner F. Kuhs, Norman Shankland and Heidrun Sowa

CrystEngComm, 2010, 12, 2354
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Mechanochemistry for facilitated access to N,N-diaryl NHC metal complexes

Audrey Beillard, Xavier Bantreil, Thomas-Xavier Métro, Jean Martinez and Frédéric Lamaty

New J. Chem., 2017, 41, 1057
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The unique opportunities of mechanosynthesis in green and scalable fabrication of metal–organic frameworks

Farzaneh Afshariazar and Ali Morsali

J. Mater. Chem. A, 2022, 10, 15332
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Mechanochemistry: opportunities for new and cleaner synthesis

Stuart L. James, Christopher J. Adams, Carsten Bolm, Dario Braga, Paul Collier, Tomislav Friščić, Fabrizia Grepioni, Kenneth D. M. Harris, Geoff Hyett, William Jones, Anke Krebs, James Mack, Lucia Maini, A. Guy Orpen, Ivan P. Parkin, William C. Shearouse, Jonathan W. Steed and Daniel C. Waddell

Chem. Soc. Rev., 2012, 41, 413
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Mechanochemical reactions of coordination polymers by grinding with KBr

Mangayarkarasi Nagarathinam, Anjana Chanthapally, Saul H. Lapidus, Peter W. Stephens and Jagadese J. Vittal

Chem. Commun., 2012, 48, 2585
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The mechanochemical synthesis of podand anion receptors

Adam N. Swinburne and Jonathan W. Steed

CrystEngComm, 2009, 11, 433
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The role of mechanochemistry and supramolecular design in the development of pharmaceutical materials

Amit Delori, Tomislav Friščić and William Jones

CrystEngComm, 2012, 14, 2350
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Coordination polymers as potential solid forms of drugs: three zinc(ii) coordination polymers of theophylline with biocompatible organic acids

Benyong Lou and Fengdan He

New J. Chem., 2013, 37, 309
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The affinity of copper(ii) ions towards l-amino acids in the solid-state: a simple route towards mixed complexes

Kristina Smokrović, Ivica Đilović and Dubravka Matković-Čalogović

CrystEngComm, 2020, 22, 4963
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Metal–organic frameworks meet scalable and sustainable synthesis

Patrick A. Julien, Cristina Mottillo and Tomislav Friščić

Green Chem., 2017, 19, 2729
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A rational approach to screen for hydrated forms of the pharmaceutical derivative magnesium naproxen using liquid-assisted grinding

Tomislav Friščić, Ivan Halasz, Fiona C. Strobridge, Robert E. Dinnebier, Robin S. Stein, László Fábián and Caroline Curfs

CrystEngComm, 2011, 13, 3125
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Isostructural coordination polymers: epitaxis vs. solid solution

Matteo Lusi, Jerry L. Atwood, Leonard R. MacGillivray and Leonard J. Barbour

CrystEngComm, 2011, 13, 4311
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Modified-amino acid/peptide pyrimidine analogs: synthesis, structural characterization and DFT studies of N-(pyrimidyl)gabapentine and N-(pyrimidyl)baclofen

Angel García-Raso, Angel Terrón, Juan J. Fiol, Adela López-Zafra, Bárbara Massanet, Antonio Frontera and Miquel Barceló-Oliver

New J. Chem., 2021, 45, 22053
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Cyclic Interconversion among Molecular Salts via Neat Grinding and Related Photoluminescence Properties

Hong-liang Liu, Yi-Fei Xie, Zhi-gang Pan, Antonino Famulari, Fang Guo, Zhongfu Zhou and Javier Martí-Rujas

Crystal Growth & Design, 2014, 14, 6528
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Synthesis, Characterization, Crystal Structure and Antimicrobial Evaluation of a Novel –M–X–M–X– Type Infinite Chain 1D Cu(II) Complex with Eflornithine Hydrochloride Hydrate as Ligand

Joshua A. Obaleye, Adedibu C. Tella, Wahab A. Osunniran, Nzikahyel Simon and Patricia F. Omojasola

J Inorg Organomet Polym, 2014, 24, 827
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Copper(II) ternary complexes with gabapentin and neurotransmitters as antiepileptic drug

M.A. Mahmoud, A.M. Abbas, S.A. Zaitone, A.M. Ammar and S.A. Sallam

Journal of Molecular Structure, 2019, 1180, 861
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Mechanochemical Preparation of Active Pharmaceutical Ingredients Monitored by In Situ Raman Spectroscopy

Irena Sović, Stipe Lukin, Ernest Meštrović, Ivan Halasz, Andrea Porcheddu, Francesco Delogu, Pier Carlo Ricci, Fabien Caron, Thomas Perilli, Anita Dogan and Evelina Colacino

ACS Omega, 2020, 5, 28663
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An ester derivative of the drug gabapentin: pH dependent crystal stability

Vânia André, M. Matilde Marques, M.F. Minas da Piedade and M. Teresa Duarte

Journal of Molecular Structure, 2010, 973, 173
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Exploring Various Crystal and Molecular Structures of Gabapentin—A Review

Justyna Baranowska and Łukasz Szeleszczuk

Crystals, 2024, 14, 257
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Recent advances of discrete coordination complexes and coordination polymers in drug delivery

Zhenbo Ma and Brian Moulton

Coordination Chemistry Reviews, 2011, 255, 1623
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Postsynthetic modification of a coordination compound with a paddlewheel motif via click reaction: DOSY and ESR studies

Shuangbing Han, Zhenbo Ma, Russell Hopson, Yanhu Wei, David Budil, Stefano Gulla and Brian Moulton

Inorganic Chemistry Communications, 2012, 15, 78
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Solid-state synthesis of isostructural tetrachlorometallate salts of amodiaquine: crystal structure of [CdCl4][C20H24ClN3O]

Adedibu C. Tella, Samson O. Owalude, Nzikahyel Simon and Rotimi O. Arise

Med Chem Res, 2015, 24, 3949
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Solvent-free synthesis, x-ray studies and in vitro inhibitory activities of copper(II) complexes of non-steroidal anti-inflammatory drugs

A. C. Tella, J. A. Obaleye, U. B. Eke, A. Y. Isaac and O. M. Ameen

Res Chem Intermed, 2014, 40, 1441
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Mechanosynthesis of the Metallodrug Bismuth Subsalicylate from Bi2O3 and Structure of Bismuth Salicylate without Auxiliary Organic Ligands

Vânia André, Andrew Hardeman, Ivan Halasz, Robin S. Stein, Graham J. Jackson, David G. Reid, Melinda J. Duer, Caroline Curfs, M. Teresa Duarte and Tomislav Friščić

Angewandte Chemie, 2011, 123, 8004
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Speciation of Copper(II)‐Betaine Complexes as Starting Point for Electrochemical Copper Deposition from Ionic Liquids

Janine Richter, Maximilian Knies and Michael Ruck

ChemistryOpen, 2021, 10, 97
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Zinc ternary complexes with gabapentin and neurotransmitters: Synthesis, spectral, thermal and molecular docking studies

M.A. Mahmoud, M.A. Helal and A.M. Ammar

Journal of Molecular Structure, 2020, 1199, 126951
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A zinc(II) quinolinone complex (Et3NH)[Zn(qui)Cl2]: Synthesis, X-ray structure, spectral properties and in vitro cytotoxicity

Roman Buchtík, Ivan Nemec and Zdeněk Trávníček

Journal of Molecular Structure, 2014, 1060, 42
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On the Track of New Multicomponent Gabapentin Crystal Forms: Synthon Competition and pH Stability

Vânia André, Auguste Fernandes, Pedro Paulo Santos and M. Teresa Duarte

Crystal Growth & Design, 2011, 11, 2325
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Solvent-free mechanochemical synthesis and X-ray studies of Cu(II) and Ni(II) complexes of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine (Trimethoprim) in a ball-mill

Adedibu C. Tella, Uche B. Eke and Samson O. Owalude

Journal of Saudi Chemical Society, 2016, 20, S376
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α-Diimine transition-metal complexes: Mechanochemistry − A new synthetic approach

Clara S.B. Gomes, Pedro T. Gomes and M. Teresa Duarte

Journal of Organometallic Chemistry, 2014, 760, 101
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Alternative Technologies That Facilitate Access to Discrete Metal Complexes

Audrey Beillard, Xavier Bantreil, Thomas-Xavier Métro, Jean Martinez and Frédéric Lamaty

Chem. Rev., 2019, 119, 7529
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Green and environmental friendly synthesis of copper (II) and nickel (II) complexes of rhodanine and its antibacterial effectiveness

Samuel A. Ajala, Adedibu Clement Tella, Idowu Olatunbosun Adeoye, Ojeyemi Matthew Olabemiwo, Babawale Emmanuel Abiola and Sunday Adewale Akintelu

Current Research in Green and Sustainable Chemistry, 2022, 5, 100318
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Green and Environmental Friendly Synthesis of Copper (II) and Nickel (II) Complexes of Rhodanine and its Antibacterial Effectiveness

Samuel A. Ajala, Adedibu Clement Tella, Idowu Adeoye, Ojeyemi Matthew Olabemiwo, Babawale Emmanuel Abiola and Sunday Akintelu

SSRN Journal, 2021
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Can mechanochemical synthesis be utilized in the progress of chemosensing technology? A case study with a series of Cu2+ selective receptors

Ratish R. Nair, Anirban Paul, M. Raju, E. Suresh, Divesh N. Srivastava and Pabitra B. Chatterjee

Sensors and Actuators B: Chemical, 2017, 253, 213
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Synthesis and characterization of mixed-ligand Co(II) complexes with gabapentin or pregabalin and diimine coligands: DNA interaction, antibacterial, antifungal and molecular docking studies

Marwa A. Mahmoud, Rawan B. Abdelrahman and Khaled M. Darwish

Journal of Molecular Structure, 2024, 1304, 137609
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A compendium of cyclic sugar amino acids and their carbocyclic and heterocyclic nitrogen analogues

Martijn Risseeuw, Mark Overhand, George W. J. Fleet and Michela I. Simone

Amino Acids, 2013, 45, 613
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Exploring mechanochemistry to turn organic bio-relevant molecules into metal-organic frameworks: a short review

Vânia André, Sílvia Quaresma, João Luís Ferreira da Silva and M Teresa Duarte

Beilstein J. Org. Chem., 2017, 13, 2416
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Investigating the Mechanism of l-Valine in Improving the Stability of Gabapentin Combining Chemical Analysis Experiments with Computational Pharmacy

Jiaxin Wang, Lixiang Yang, Daixi Li, Ying Xu, Li Yang, Hong Zhao, Zhuangzhi Zhu, Hansen Luan and Qiong Luo

AAPS PharmSciTech, 2019, 20
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Crystal Structures of a New Polymorphic Form of Gabapentin Monohydrate and the E and Z Isomers of 4‐Tertiarybutylgabapentin

Prema G. Vasudev, Subrayashastry Aravinda, Kuppanna Ananda, Shettykere Dayananda Veena, Kuppuswamy Nagarajan, Narayanaswamy Shamala and Padmanabhan Balaram

Chem Biol Drug Des, 2009, 73, 83
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Studies of the molecular docking, antibacterial, antifungal, and DNA interaction of mixed-ligand Ni(II) complexes with gabapentin or pregabalin and diimine coligands

Marwa A. Mahmoud, Shehab A. Sallam, Rawan B. Abdelrahman and Abbas M. Abbas

Inorganica Chimica Acta, 2024, 564, 121959
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A gold(III) complex and a tetrachloroaurate salt of the neuroepileptic drug gabapentin

Ahmed Shaikjee, Demetrius C. Levendis, Helder M. Marques and Richard Mampa

Inorganic Chemistry Communications, 2011, 14, 534
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One‐Pot Mechanosynthesis with Three Levels of Molecular Self‐Assembly: Coordination Bonds, Hydrogen Bonds and Host–Guest Inclusion

Tomislav Friščić, Ernest Meštrović, Dijana Škalec Šamec, Branko Kaitner and László Fábián

Chemistry A European J, 2009, 15, 12644
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Advances in Solid-State Transformations of Coordination Bonds: From the Ball Mill to the Aging Chamber

Cristina Mottillo and Tomislav Friščić

Molecules, 2017, 22, 144
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Cocrystals and Salts of Gabapentin: pH Dependent Cocrystal Stability and Solubility

L. Sreenivas Reddy, Sarah J. Bethune, Jeff W. Kampf and Naír Rodríguez-Hornedo

Crystal Growth & Design, 2009, 9, 378
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Tetraaquatetrakis{μ2-[1-(carboxylatomethyl)cyclohexyl]methanaminium}bis(μ3-hydroxido)bis(nitrato-κ2O,O′)tetrazinc(II)

Elise J. C. de Vries, Caryn Gamble and Ahmed Shaikjee

Acta Crystallogr E Struct Rep Online, 2011, 67, m573
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Template metal-organic frameworks: solvent-free synthesis, characterization and powder X-ray diffraction studies of [Cu(NO3)2(bipy)2](py)2

Adedibu C. Tella, Olanrewaju A. Ameen, Peter A. Ajibade and Lukman O. Alimi

J Porous Mater, 2015, 22, 1599
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Two copper(II) coordination complexes based on sulfanilamide ligand: Synthesis, structure, thermal analyzes, electrochemical properties and biological activities

Oussama Chebout, Rafika Bouchene, Sofiane Bouacida, M'hamed Boudraa, Wissam Mazouz, Moufida Merzougui, Kamel Ouari, Chaouki Boudaren and Hocine Merazig

Journal of Molecular Structure, 2022, 1247, 131346
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Mechanosynthesis of the Metallodrug Bismuth Subsalicylate from Bi2O3 and Structure of Bismuth Salicylate without Auxiliary Organic Ligands

Vânia André, Andrew Hardeman, Ivan Halasz, Robin S. Stein, Graham J. Jackson, David G. Reid, Melinda J. Duer, Caroline Curfs, M. Teresa Duarte and Tomislav Friščić

Angew Chem Int Ed, 2011, 50, 7858
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Gabapentin Coordination Networks: Mechanochemical Synthesis and Behavior under Shelf Conditions

Sílvia Quaresma, Vânia André, Alexandra M. M. Antunes, Luís Cunha-Silva and M. Teresa Duarte

Crystal Growth & Design, 2013, 13, 5007
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Mechanochemistry – A green synthetic methodology leading to metallodrugs, metallopharmaceuticals and bio-inspired metal-organic frameworks

Sílvia Quaresma, Vânia André, Auguste Fernandes and M. Teresa Duarte

Inorganica Chimica Acta, 2017, 455, 309
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Instant Detection of Hydrogen Cyanide Gas and Cyanide Salts in Solid Matrices and Water by using CuII and NiII Complexes of Intramolecularly Hydrogen Bonded Zwitterions

Ratish R. Nair, M. Raju, Kalyanashis Jana, Dhrubajyoti Mondal, E. Suresh, Bishwajit Ganguly and Pabitra B. Chatterjee

Chemistry A European J, 2018, 24, 10721
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Hydrogen Bonding Patterns of the Co-Crystal Containing the Pharmaceutically Active Ingredient Isoniazid and Terephthalic Acid

Andreas Lemmerer, Joel Bernstein and Volker Kahlenberg

J Chem Crystallogr, 2011, 41, 991
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New forms of old drugs: improving without changing

Sofia Domingos, Vânia André, Sílvia Quaresma, Inês C B Martins, M Fátima Minas da Piedade and Maria Teresa Duarte

Journal of Pharmacy and Pharmacology, 2015, 67, 830
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