Issue 36, 2011
From the journal:

Chemical Communications

A fluoro analogue of UDP-α-d-glucuronic acid is an inhibitor of UDP-α-d-apiose/UDP-α-d-xylose synthase†‡

Sei-hyun Choi,a   Mark W. Ruszczycky,b   Hua Zhangb  and  Hung-wen Liu*ab  

* Corresponding authors

a Department of Chemistry and Biochemistry, University of Texas at Austin, Texas 78712, Austin, USA
E-mail: h.w.liu@mail.utexas.edu
Tel: +1 512-232-7811

b Medicinal Chemistry Division, College of Pharmacy, University of Texas at Austin, Texas 78712, Austin, USA

Abstract

UDP-2F-glucuronic acid was synthesized and analyzed as a mechanistic probe to investigate the ring contraction step catalyzed by UDP-D-apiose/UDP-D-xylose synthase (AXS).

Graphical abstract: A fluoro analogue of UDP-α-d-glucuronic acid is an inhibitor of UDP-α-d-apiose/UDP-α-d-xylose synthase

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1CC13140K
Article type
Communication
Submitted
27 mei 2011
Accepted
20 jul 2011
First published
09 aug 2011

Chem. Commun., 2011,47, 10130-10132

Permissions

Request permissions

A fluoro analogue of UDP-α-D-glucuronic acid is an inhibitor of UDP-α-D-apiose/UDP-α-D-xylose synthase

S. Choi, M. W. Ruszczycky, H. Zhang and H. Liu, Chem. Commun., 2011, 47, 10130 DOI: 10.1039/C1CC13140K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements