Issue 37, 2022

Latest on biomaterial-based therapies for topical treatment of psoriasis

Abstract

Psoriasis is an autoimmune inflammatory disease which is fundamentally different from dermatitis. Its treatments include topical medications and systemic drugs depending on different stages of the disease. However, these commonly used therapies are falling far short of clinical needs due to various drawbacks. More precise therapeutic strategies with minimized side effects and improved compliance are highly demanded. Recently, the rapid development of biomaterial-based therapies has made it possible and promising to attain topical psoriasis treatment. In this review, we briefly describe the significance and challenges of the topical treatment of psoriasis and emphatically overview the latest progress in novel biomaterial-based topical therapies for psoriasis including microneedles, nanoparticles, nanofibers, and hydrogels. Current clinical trials related to each biomaterial are also summarized and discussed.

Graphical abstract: Latest on biomaterial-based therapies for topical treatment of psoriasis

Article information

Article type
Review Article
Submitted
21 mrt 2022
Accepted
25 mei 2022
First published
09 jun 2022

J. Mater. Chem. B, 2022,10, 7397-7417

Latest on biomaterial-based therapies for topical treatment of psoriasis

A. Chen, Y. Luo, J. Xu, X. Guan, H. He, X. Xuan and J. Wu, J. Mater. Chem. B, 2022, 10, 7397 DOI: 10.1039/D2TB00614F

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