Issue 21, 2021

Functionalization of imidazo[1,2-a]pyridines via radical reactions

Abstract

Imidazo[1,2-a]pyridines are a class of valuable heterocyclic scaffolds in organic synthesis and pharmaceutical chemistry. The direct functionalization of this valuable scaffold has been considered as one of the most efficient strategies for the construction of imidazo[1,2-a]pyridine derivatives. This review summarizes the recent advances in radical reactions for the direct functionalization of imidazo[1,2-a]pyridines through transition metal catalysis, metal-free oxidation, and photocatalysis strategies.

Graphical abstract: Functionalization of imidazo[1,2-a]pyridines via radical reactions

Article information

Article type
Perspective
Submitted
10 feb 2021
Accepted
21 apr 2021
First published
21 apr 2021

New J. Chem., 2021,45, 9302-9314

Functionalization of imidazo[1,2-a]pyridines via radical reactions

C. Ma, M. Chen, Z. Feng, Y. Zhang, J. Wang, Y. Jiang and B. Yu, New J. Chem., 2021, 45, 9302 DOI: 10.1039/D1NJ00704A

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