Issue 6, 2021

Real-time monitoring of crystallization from solution by using an interdigitated array electrode sensor

Abstract

Monitoring crystallization events in real-time is challenging but crucial for understanding the molecular dynamics associated with nucleation and crystal growth, some of nature's most ubiquitous phenomena. Recent observations have suggested that the traditional nucleation model, which describes the nucleus having already the final crystal structure, may not be valid. It appears that the molecular assembly can range during nucleation from crystalline to partially ordered to totally amorphous phases, and can change its structure during the crystallization process. Therefore, it is of critical importance to develop methods that are able to provide real-time monitoring of the molecular interactions with high temporal resolution. Here, we demonstrate that a simple and scalable approach based on interdigitated electrode array sensors (IESs) is able to provide insights on the dynamics of the crystallization process with a temporal resolution of 15 ms.

Graphical abstract: Real-time monitoring of crystallization from solution by using an interdigitated array electrode sensor

Supplementary files

Article information

Article type
Communication
Submitted
10 dec 2020
Accepted
08 apr 2021
First published
21 apr 2021
This article is Open Access
Creative Commons BY-NC license

Nanoscale Horiz., 2021,6, 468-473

Real-time monitoring of crystallization from solution by using an interdigitated array electrode sensor

J. Tong, A. Doumbia, M. L. Turner and C. Casiraghi, Nanoscale Horiz., 2021, 6, 468 DOI: 10.1039/D0NH00685H

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