Issue 37, 2020

Nanoscopic insights into the surface conformation of neurotoxic amyloid β oligomers

Abstract

Raman spectroscopy assisted by localized plasmon resonances generating effective hot spots at the gaps between intertwined silver nanowires is herein adopted to unravel characteristic molecular motifs on the surface of Aβ42 misfolded oligomers that are critical in driving intermolecular interactions in neurodegeneration.

Graphical abstract: Nanoscopic insights into the surface conformation of neurotoxic amyloid β oligomers

Supplementary files

Article information

Article type
Paper
Submitted
27 apr 2020
Accepted
01 jun 2020
First published
08 jun 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 21907-21913

Nanoscopic insights into the surface conformation of neurotoxic amyloid β oligomers

M. Banchelli, R. Cascella, C. D'Andrea, L. Cabaj, I. Osticioli, D. Ciofini, M. S. Li, K. Skupień, M. de Angelis, S. Siano, C. Cecchi, R. Pini, G. La Penna, F. Chiti and P. Matteini, RSC Adv., 2020, 10, 21907 DOI: 10.1039/D0RA03799K

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