nBuLi-promoted anti-Markovnikov selective hydroboration of unactivated alkenes and internal alkynes†
Shi-Liang
Shi 
*b
and
Youjun
Xu
*a
*b
and
Youjun
Xu
*a
Abstract
An efficient and general nBuLi-promoted anti-Markovnikov selective hydroboration of various α-alkenes, 1,1-disubstituted alkenes and internal alkynes with pinacolborane for the synthesis of alkylboronic esters is described. This protocol features easy accessibility of catalysts and substrates, a broad substrate scope, and simple operation as well as scale-up ability.
- This article is part of the themed collection: Celebrating 70 Years of Shanghai Institute of Organic Chemistry
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