Issue 6, 2015

Copper-catalysed cross-couplings of arylboronate esters with aryl and heteroaryl iodides and bromides

Abstract

CuI-catalysed coupling of arylboronate esters with aryl and heteroaryl iodides and bromides is described. The transformation affords products in good yields using 5–10 mol% catalyst loadings. The described reaction requires a P,N-based bidentate ligand in combination with CuI for aryl–aryl coupling, but it proceeds without external ligands for aryl–heteroaryl coupling to afford the products. The reaction protocol can also be applied to achieve biarylation of diiodoarenes in reasonable yields.

Graphical abstract: Copper-catalysed cross-couplings of arylboronate esters with aryl and heteroaryl iodides and bromides

Supplementary files

Article information

Article type
Research Article
Submitted
16 dec 2014
Accepted
14 feb 2015
First published
16 feb 2015

Org. Chem. Front., 2015,2, 649-653

Author version available

Copper-catalysed cross-couplings of arylboronate esters with aryl and heteroaryl iodides and bromides

S. K. Gurung, S. Thapa, B. Shrestha and R. Giri, Org. Chem. Front., 2015, 2, 649 DOI: 10.1039/C4QO00331D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements