Issue 2, 2015

Difluoromethyl 2-pyridyl sulfone: a versatile carbonyl gem-difluoroolefination reagent

Abstract

This tutorial account describes a robust carbonyl gem-difluoroolefination reagent, difluoromethyl 2-pyridyl sulfone (2-PySO2CF2H), developed by our group, recently. The guidelines for its laboratory preparation and application are presented in detail for potential users.

Graphical abstract: Difluoromethyl 2-pyridyl sulfone: a versatile carbonyl gem-difluoroolefination reagent

Article information

Article type
Tutorial Account
Submitted
06 nov 2014
Accepted
12 dec 2014
First published
16 dec 2014

Org. Chem. Front., 2015,2, 163-168

Difluoromethyl 2-pyridyl sulfone: a versatile carbonyl gem-difluoroolefination reagent

B. Gao, Y. Zhao, J. Hu and J. Hu, Org. Chem. Front., 2015, 2, 163 DOI: 10.1039/C4QO00291A

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