Issue 21, 2013
From the journal:

Organic & Biomolecular Chemistry

Towards a dynamic covalent molecular switch: substituent effects in chalcone/flavanone isomerism†

Jesse Mai,a   Ermal Hoxha,a   Caitlin E. Morton,a   Brian M. Mullera  and  Marc J. Adler*a  

* Corresponding authors

a Department of Chemistry & Biochemistry, Northern Illinois University, 1425 W. Lincoln Hwy., DeKalb, IL, USA
E-mail: mjadler@niu.edu
Fax: +1 815 753 4802
Tel: +1 815 753 9236

Abstract

Chalcone/flavanone interconversion occurs facilely under aqueous alkaline conditions making it a promising scaffold for the development of a covalent molecular switch. In this study, a single methoxy substituent is shown to have a significant impact on the equilibrium dynamics of this reaction; this impact is dependent on the site of substitution.

Graphical abstract: Towards a dynamic covalent molecular switch: substituent effects in chalcone/flavanone isomerism

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3OB40467F
Article type
Communication
Submitted
07 mrt 2013
Accepted
12 mrt 2013
First published
18 mrt 2013

Org. Biomol. Chem., 2013,11, 3421-3423

Permissions

Request permissions

Towards a dynamic covalent molecular switch: substituent effects in chalcone/flavanone isomerism

J. Mai, E. Hoxha, C. E. Morton, B. M. Muller and M. J. Adler, Org. Biomol. Chem., 2013, 11, 3421 DOI: 10.1039/C3OB40467F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements