Issue 34, 2016

Acetazolamide polymorphism: a case of hybridization induced polymorphism?

Abstract

The unusual phenomenon of the formation of the kinetic form as against the thermodynamic form upon slow cooling of boiling aqueous solution in the case of diuretic drug acetazolamide is rationalized in terms of “hybridization induced polymorphism” based on extensive experimental and theoretical investigations.

Graphical abstract: Acetazolamide polymorphism: a case of hybridization induced polymorphism?

Supplementary files

Article information

Article type
Communication
Submitted
22 feb 2016
Accepted
17 mrt 2016
First published
21 mrt 2016

Chem. Commun., 2016,52, 5820-5823

Acetazolamide polymorphism: a case of hybridization induced polymorphism?

S. Sarkar, M. S. Pavan, S. Cherukuvada and T. N. Guru Row, Chem. Commun., 2016, 52, 5820 DOI: 10.1039/C6CC01612J

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