Issue 38, 2016

Diselenide-based probe for the selective imaging of hypochlorite in living cancer cells

Abstract

A non-traditional and robust probe skeleton was derivatized for chemosensing applications to investigate a potential novel mode of hypochlorite detection. The BDPP-DSe probe gave a ∼180-fold “turn-on” response to hypochlorite. Confocal fluorescence imaging demonstrated detection of hypochlorite in living cells and cell membrane permeability.

Graphical abstract: Diselenide-based probe for the selective imaging of hypochlorite in living cancer cells

Supplementary files

Article information

Article type
Communication
Submitted
17 feb 2016
Accepted
22 mrt 2016
First published
24 mrt 2016

RSC Adv., 2016,6, 32013-32017

Diselenide-based probe for the selective imaging of hypochlorite in living cancer cells

Y. Kim, M. Choi, S. T. Manjare, S. Jon and D. G. Churchill, RSC Adv., 2016, 6, 32013 DOI: 10.1039/C6RA04257K

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