Issue 10, 2024

Multifunctional antibacterial hydrogels for chronic wound management

Abstract

Chronic wounds have gradually evolved into a global health challenge, comprising long-term non-healing wounds, local tissue necrosis, and even amputation in severe cases. Accordingly, chronic wounds place a considerable psychological and economic burden on patients and society. Chronic wounds have multifaceted pathogenesis involving excessive inflammation, insufficient angiogenesis, and elevated reactive oxygen species levels, with bacterial infection playing a crucial role. Hydrogels, renowned for their excellent biocompatibility, moisture retention, swelling properties, and oxygen permeability, have emerged as promising wound repair dressings. However, hydrogels with singular functions fall short of addressing the complex requirements associated with chronic wound healing. Hence, current research emphasises the development of multifunctional antibacterial hydrogels. This article reviews chronic wound characteristics and the properties and classification of antibacterial hydrogels, as well as their potential application in chronic wound management.

Graphical abstract: Multifunctional antibacterial hydrogels for chronic wound management

Article information

Article type
Review Article
Submitted
28 jan 2024
Accepted
25 mrt 2024
First published
05 apr 2024
This article is Open Access
Creative Commons BY license

Biomater. Sci., 2024,12, 2460-2479

Multifunctional antibacterial hydrogels for chronic wound management

Y. Hu, L. Yu, Q. Dai, X. Hu and Y. Shen, Biomater. Sci., 2024, 12, 2460 DOI: 10.1039/D4BM00155A

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