Issue 33, 2020

Recent progress in chemosensors based on pyrazole derivatives

Abstract

Colorimetric and fluorescent probes based on small organic molecules have become important tools in modern biology because they provide dynamic information concerning the localization and quantity of the molecules and ions of interest without the need for genetic engineering of the sample. In the past five years, these probes for ions and molecules have attracted great attention because of their biological, environmental and industrial significance combined with the simplicity and high sensitivity of absorption and fluorescence techniques. Moreover, pyrazole derivatives display a number of remarkable photophysical properties and wide synthetic versatility superior to those of other broadly used scaffolds. This review provides an overview of the recent (2016–2020) findings on chemosensors containing pyrazole derivatives (pyrazoles, pyrazolines and fused pyrazoles). The discussion focuses on the design and physicochemical properties of chemosensors in order to realize their full potential for practical applications in environmental and biological monitoring (sensing of metal ions, anions, explosives, and biomolecules). We also present our conclusions and outlook for the future.

Graphical abstract: Recent progress in chemosensors based on pyrazole derivatives

Article information

Article type
Review Article
Submitted
14 mrt 2020
Accepted
19 mei 2020
First published
22 mei 2020
This article is Open Access
Creative Commons BY license

RSC Adv., 2020,10, 19693-19712

Recent progress in chemosensors based on pyrazole derivatives

A. Tigreros and J. Portilla, RSC Adv., 2020, 10, 19693 DOI: 10.1039/D0RA02394A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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