Issue 7, 2018

Application of a rhodium-catalyzed cyclization cycloaddition cascade strategy to the total synthesis of (−)-curcumol

Abstract

A de novo asymmetric total synthesis of (−)-curcumol has been realized, based on a rhodium-catalyzed cyclization–cycloaddition cascade reaction as the key step to construct the tricyclic nucleus.

Graphical abstract: Application of a rhodium-catalyzed cyclization cycloaddition cascade strategy to the total synthesis of (−)-curcumol

Supplementary files

Article information

Article type
Research Article
Submitted
23 dec 2017
Accepted
23 jan 2018
First published
23 jan 2018

Org. Chem. Front., 2018,5, 1092-1095

Application of a rhodium-catalyzed cyclization cycloaddition cascade strategy to the total synthesis of (−)-curcumol

X. X. Zhang, R. Y. Y. Ko, X. Q. Xie, W. P. Qi, P. C. Li and P. Chiu, Org. Chem. Front., 2018, 5, 1092 DOI: 10.1039/C7QO01150D

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