Issue 2, 2018

A fluorescent activatable probe for imaging intracellular Mg2+

Abstract

An activatable BODIPY probe for in vitro detection and fluorescence cell imaging of free Mg2+ without interference from Ca2+ is described. Fluorescence amplification of the probe is observed upon detection of physiological concentrations of Mg2+ due to reduced rotation of the fluorophore and effective chelation by a quinolizine-based core.

Graphical abstract: A fluorescent activatable probe for imaging intracellular Mg2+

Supplementary files

Article information

Article type
Paper
Submitted
01 dec 2017
Accepted
12 dec 2017
First published
19 dec 2017
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2018,16, 239-244

A fluorescent activatable probe for imaging intracellular Mg2+

R. Treadwell, F. de Moliner, R. Subiros-Funosas, T. Hurd, K. Knox and M. Vendrell, Org. Biomol. Chem., 2018, 16, 239 DOI: 10.1039/C7OB02965A

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