Issue 4, 2018

Graphene quantum dots based fluorescence turn-on nanoprobe for highly sensitive and selective imaging of hydrogen sulfide in living cells

Abstract

Hydrogen sulfide (H2S), being an important gaseous signaling molecule, has been gaining increasing attention for its involvement in a wide range of physiological processes. Herein, we developed a novel fluorescence turn-on nanoprobe for selective and sensitive detection of H2S based on graphene quantum dots (GQDs) conjugated with (2,4-dinitrophenoxy)tyrosine (DNPTYR). Taking advantage of its high fluorescence quantum yield, biocompatibility, photostability, and ease to be uptaken by cells, the GQD-based fluorescence probe was further employed for real-time monitoring of the triggered dynamic change of the intracellular H2S level in live cells.

Graphical abstract: Graphene quantum dots based fluorescence turn-on nanoprobe for highly sensitive and selective imaging of hydrogen sulfide in living cells

Supplementary files

Article information

Article type
Paper
Submitted
05 sep 2017
Accepted
31 okt 2017
First published
01 nov 2017

Biomater. Sci., 2018,6, 779-784

Graphene quantum dots based fluorescence turn-on nanoprobe for highly sensitive and selective imaging of hydrogen sulfide in living cells

N. Li, A. Than, J. Chen, F. Xi, J. Liu and P. Chen, Biomater. Sci., 2018, 6, 779 DOI: 10.1039/C7BM00818J

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