Issue 12, 2017

Selectively lighting up two-photon photodynamic activity in mitochondria with AIE-active iridium(iii) complexes

Abstract

Herein a series of mitochondria-targeted AIE (aggregation-induced emission)-active Ir(III) complexes were designed to selectively exert one-/two-photon photodynamic activities in mitochondria to address the issues which current PDT are confronted with (i.e., shallow penetration depth of routinely used irradiation; systematic toxicity associated with effective drug concentration; concentration-quenched photodynamic activity at the target, etc.).

Graphical abstract: Selectively lighting up two-photon photodynamic activity in mitochondria with AIE-active iridium(iii) complexes

Supplementary files

Article information

Article type
Communication
Submitted
16 dec 2016
Accepted
18 jan 2017
First published
18 jan 2017

Chem. Commun., 2017,53, 2052-2055

Selectively lighting up two-photon photodynamic activity in mitochondria with AIE-active iridium(III) complexes

J. Liu, C. Jin, B. Yuan, X. Liu, Y. Chen, L. Ji and H. Chao, Chem. Commun., 2017, 53, 2052 DOI: 10.1039/C6CC10015E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements