Daniel Braatz, Justus H. Peter, Mathias Dimde, Elisa Quaas, Kai Ludwig, Katharina Achazi, Michael Schirner, Matthias Ballauff and Rainer Haag
J. Mater. Chem. B, 2023,11, 3797-3807
Abstract
Highly stable micelles are facilitated by π–π interactions in an amphiphilic block copolymer system consisting of dPGS-SS-POxPPh-Py, where each building block contributes a particular ability.
Hanne Verschuere, Sabah Kasmi, Lutz Nuhn, Sènan Mickaël D'Almeida, Qiwen Zhu, Zifu Zhong, Sandy Adjemian, Benoit Louage, Jana De Vrieze, Haijun Yu, Bruno G. De Geest and Peter Vandenabeele
RSC Adv., 2025,15, 11662-11674
Abstract
Combining a cytotoxic drug with an immune-activating drug eradicates tumors.
Meihui Su, Xin Wen, Yunjian Yu, Na Li, Xiaohui Li, Xiongwei Qu, Mahmoud Elsabahy and Hui Gao
J. Mater. Chem. B, 2024,12, 3947-3958
From themed collection:
2024 Journal of Materials Chemistry B HOT Papers
Abstract
The tailored nanomedicine 5-FU-LA@PPL could selectively combat Fn, inhibit autophagy in CRC cells, restore chemosensitivity of 5-FU as well as OxPt, and consequently enhance the combination chemotherapy effects for Fn-associated drug-resistant CRC.
Jiao Xia Zou, Meng Rui Chang, Nikita A. Kuznetsov, Jia Xuan Kee, Maria V. Babak and Wee Han Ang
Chem. Sci., 2025,16, 6160-6187
From themed collection:
2025 Chemical Science Perspective & Review Collection
Abstract
A comprehensive review of metal-based inducers of immunogenic cell death (ICD), their design strategies, molecular mechanisms to trigger ICD, subsequent protective antitumor immune responses, as well as validation approaches.
Linming Li, Yan Chen, Ming Zhang, Suying Li, Shuaiqi Feng, Yan-Qin He, Ning Zhang, Zhifang Liu, Meifeng Liu and Qingpeng Wang
Dalton Trans., 2024,53, 13890-13905
Abstract
A hydroxychloroquine platinum(IV) complex targeting autophagy was developed as an antitumor agent with promising antiproliferative and antimetastatic activities.