Fluorescent molecular rotors incorporating julolidine have found diverse applications in various research fields.
Alkylation at the O6 position of guanine is a common and highly mutagenic form of DNA damage. Here, dynamic changes in fluorescence from a molecular rotor base analogue are used to track O6 alkylation and repair in duplex DNA.
This review examines peptide-conjugated fluorescent molecular rotors (FMRs) for protein detection. Their application are also highlighted for quantifying expression, monitoring structural alterations, and detecting intermolecular interactions.
Ratiometric fluorescent viscosity sensors based on BODIPY and coumarin fluorophores are presented, featuring an ester bridge aimed at minimizing the influence of polarity, thus leading to improved analytical responses within a wide viscosity range.
This review focusses on the significance of fluorescent, phosphorescent labelling and tracking of extracellular vesicles (EVs) for unravelling their biology, pathophysiology, and potential diagnostic and therapeutic uses.