Visible-light-induced hydroxycarboxylation of α-trifluoromethylstyrenes under an air atmosphere was developed to construct densely functionalized α-CF3 tertiary alcohols.
A practical strategy for the photoinduced defluorinative alkylation of α-trifluoromethyl styrenes with carbonyl derivatives via C–C bond cleavage was disclosed.
Radical defluorinative functionalization of α-trifluoromethyl styrenes represents an effective way toward gem-difluoroalkenes.
A practical, environmentally friendly, visible-light-driven and EDA complex-promoted method for the synthesis of α-trifluoromethyl-β-phosphorodithioate tertiary alcohols in the absence of metals, photocatalysts and oxidants has been reported.
A base-controlled synthesis of N-β-CF3-substituted 2H-benzo[d]imidazole-2-thiones and 2-fluoro-4H-benzo[4,5]imidazo[2,1-b][1,3]thiazines via hydroamination or defluorinative cyclizations of α-CF3-styrenes with 2-mercaptobenzimidazole was developed.