TMS-ethers of the CF3-benzyl type alcohols of the thiophene and (benzo)furan series undergo transformations in TfOH, leading to the formation of various products of side chain arylation, dehalogenation, arylation of the heteroaromatic core, and others.
Synthesis and characterization of several chiral, oxazoline containing β-diketiminate type ligand supported-aluminium compounds are reported as well as their catalytic properties for difficult Diels-Alder cyclisation reactions.
A sequence of novel acrylic acids and acrylic esters has been synthesized and evaluated for in vitro cytotoxicity against MCF-7 breast cancer cells.
The synthesis of a variety of NHC- and cAAC-ligated cationic copper(I) complexes in their salts with the weakly coordinating tris(pentafluoroethyl)trifluorophosphate counteranion (FAP− anion, [(C2F5)3PF3]−) is reported.
Analogues of imatinib and nilotinib, where the pyridine ring is replaced by a ferrocenyl moiety, were synthesized and evaluated for their anti-cancer activity. Two of the metallocenes exhibited highly selective tumor cell growth inhibition.