This review describes the chemistry of new HOPO based chelators and their complexes in terms of their use as sensors and sensitizers.
(Eu3+4[PTC]4–3)0.78(Eu3+[TREN-1,2-HOPO]3−)0.22 nanoparticles show a shift of the emission colour from red to green triggered by carbonate, allowing a luminescence-driven qualitative and quantitative determination of the carbonate content in water.
The mammalian protein siderocalin binds hydroxypyridinone complexes of trivalent rare-earth metals and f-elements through cation-π and electrostatic interactions. It can also be fused with biological vectors for the targeted delivery of imaging and therapeutic radionuclides.
A high-throughput workflow leveraging equivariant GNNs and a diverse dataset of rare-earth complexes to predict binding affinities and accelerate critical metal separation.
A schematic diagram illustrates how OPO protects against DSS-induced colitis by modulating gut microbiota, enhancing intestinal epithelial barrier integrity, and subsequently downregulating the TLR4-MyD88-NF-κB signaling pathway.