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Heparin-based hydrogels with tunable sulfation & degradation for anti-inflammatory small molecule delivery

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Intra-articular TSG-6 delivery from heparin-based microparticles reduces cartilage damage in a rat model of osteoarthritis

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Biomater. Sci., 2018, 6, 1159
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Degradable Poly(Methyl Methacrylate)-co-Methacrylic Acid Nanoparticles for Controlled Delivery of Growth Factors for Bone Regeneration

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Sweet but Challenging: Tackling the Complexity of GAGs with Engineered Tailor‐Made Biomaterials

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Advanced Materials, 2024, 36
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Multifunctional Porous Microshuttles as Scaffolding Components and Carriers of Bioactive Factors in Self‐Assembled Microtissues

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Regional SDF-1α Delivery to Injured Rotator Cuff Muscle Causes Localized Changes in Inflammatory Cell Response

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Heparinized Polyurethane/Polycaprolactone Nanofibers via Oxygen Plasma for Enhanced Endothelialization And Angiogenesis in Small-Diameter Grafts

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Glycosaminoglycan-based biomaterials for growth factor and cytokine delivery: Making the right choices

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Sulfation of Glycosaminoglycan Hydrogels Instructs Cell Fate and Chondral versus Endochondral Lineage Decision of Skeletal Stem Cells In Vivo

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Adv Funct Materials, 2022, 32
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Affinity-controlled release of rod-derived cone viability factor enhances cone photoreceptor survival

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Acta Biomaterialia, 2023, 161, 37
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Modulated Protein Delivery to Engineer Tissue Repair

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Tissue Engineering Part A, 2019, 25, 925
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Bisphosphonate-Conjugated Photo-Crosslinking Polyanionic Hyaluronic Acid Microbeads for Controlled BMP2 Delivery and Enhanced Bone Formation Efficacy

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Biomacromolecules, 2021, 22, 4138
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Development and Characterization of Heparin-Containing Hydrogel/3D-Printed Scaffold Composites for Craniofacial Reconstruction

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Ann Biomed Eng, 2024, 52, 2287
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Hydrogel Culture Surface Stiffness Modulates Mesenchymal Stromal Cell Secretome and Alters Senescence

Molly E. Ogle, Gilad Doron, Matthew J. Levy and Johnna S. Temenoff

Tissue Engineering Part A, 2020, 26, 1259
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A Critical Review on Glycosaminoglycan Derived Polymers as a Novel Drug Delivery System in Tissue Engineering: Recent Advancement and Clinical Application

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Localized SDF-1α Delivery Increases Pro-Healing Bone Marrow-Derived Cells in the Supraspinatus Muscle Following Severe Rotator Cuff Injury

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Development and characterization of Factor Xa‐responsive materials for applications in cell culture and biologics delivery

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J Biomedical Materials Res, 2023, 111, 634
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Precisely Localized Bone Regeneration Mediated by Marine‐Derived Microdroplets with Superior BMP‐2 Binding Affinity

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Materials-based nanotherapeutics for injured and diseased bone

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Microgels based on Infernan, a glycosaminoglycan-mimetic bacterial exopolysaccharide, as BMP-2 delivery systems

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Core-shell microparticles for protein sequestration and controlled release of a protein-laden core

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Acta Biomaterialia, 2017, 56, 91
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Spatially localized recruitment of anti-inflammatory monocytes by SDF-1α-releasing hydrogels enhances microvascular network remodeling

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Biomaterials, 2016, 77, 280
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Bone Marrow Mobilization and Local Stromal Cell-Derived Factor-1α Delivery Enhances Nascent Supraspinatus Muscle Fiber Growth

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Biomaterial-guided immobilization and osteoactivity of bone morphogenetic protein-2

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Applied Materials Today, 2020, 19, 100599
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The Auxiliary Role of Heparin in Bone Regeneration and its Application in Bone Substitute Materials

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Heparin-mediated delivery of bone morphogenetic protein-2 improves spatial localization of bone regeneration

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Sci. Adv., 2020, 6
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Glycosaminoglycans exhibit distinct interactions and signaling with BMP2 according to their nature and localization

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Dual Affinity Heparin-Based Hydrogels Achieve Pro-Regenerative Immunomodulation and Microvascular Remodeling

Molly E. Ogle, Jack R. Krieger, Liane E. Tellier, Jennifer McFaline-Figueroa, Johnna S. Temenoff and Edward A. Botchwey

ACS Biomater. Sci. Eng., 2018, 4, 1241
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Heparin-based hydrogels induce human renal tubulogenesis in vitro

Heather M. Weber, Mikhail V. Tsurkan, Valentina Magno, Uwe Freudenberg and Carsten Werner

Acta Biomaterialia, 2017, 57, 59
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Directed Evolution Enables Simultaneous Controlled Release of Multiple Therapeutic Proteins from Biopolymer‐Based Hydrogels

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