Themed collection Nanoparticle-based cancer therapies

Nanoparticles utilized in targeting retinoblastoma cells demonstrated improved uptake and intracellular internalization, sustained retention, excellent cytotoxicity, enhanced apoptosis and improved antitumor activity.

This review article discusses the latest formulation methodologies and strategies for the targeted delivery of lipid nanoparticles and cell-derived nanovesicles to achieve efficient gene transfection with minimized side effects.

This review article demonstrated nucleic acid-based therapeutics and lipid nanoparticle type as a carrier of nucleic acid therapeutics for further applications of LNPs as flexible carriers in immuno-therapeutics and anti-cancer reagents.

To improve cancer treatment, various organic and inorganic nanomedicine has been studied widely combining chemo-, photodynamic-, photothermal-, radio-, and immunotherapy.

HER-2 targeted boron nitride nanotube was developed as a boron agent for boron neutron capture therapy.

Glyconanoparticles selectively bind to cellular targets via glycan–lectin interactions and are excellent drug-delivery systems for targeted photodynamic therapy of cancer.

Lipid nanocapsules was used as thymoquinone nano delivery system to treat colorectal cancer (CRC). TQ-LNCs show a suitable mean size particle and a high drug payload, inducing an early decrease in tumor growth following intratumoral administration to mice.

Chitosan ultrapure silicon nanoparticles produced by femtosecond laser ablation exhibited an ideal biodistribution profile within tumor microenvironment promising their application in the nano-oncology field as tumor targeting system.