Themed collection Lab on a Chip HOT Articles 2024
![](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/Ajax-GA-Loader.gif)
Democratizing Digital Microfluidics by a Cloud-based Design and Manufacturing Platform
Lab Chip, 2024, Accepted Manuscript
https://doi.org/10.1039/D4LC00495G
Single cell glucose-stimulated insulin secretion assay using nanowell-in-microwell plates
We develop an assay to measure glucose-stimulated insulin secretion from single cells using nanowell-in-microwells. Our results reveal the heterogeneity of single cell function for both stem cell derived β cells and human islet cells.
Lab Chip, 2024, Advance Article
https://doi.org/10.1039/D4LC00413B
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Quantitative reagent monitoring in paper-based electrochemical rapid diagnostic tests
Exploiting non-faradaic signals from electrochemical sensors to track reagent flow in rapid diagnostic tests: towards smart tests with reduced user errors.
Lab Chip, 2024,24, 3651-3657
https://doi.org/10.1039/D4LC00390J
Efficient discovery of antibody binding pairs using a photobleaching strategy for bead encoding
The paper introduces a photobleaching strategy for producing multiple bead populations on flow cytometry to accelerate and facilitate the discovery of antibody-binding pairs using a pooled antibody cross-testing assay.
Lab Chip, 2024,24, 4060-4072
https://doi.org/10.1039/D4LC00382A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Monomeric and oligomeric amyloid-β cause distinct Alzheimer's disease pathophysiological characteristics in astrocytes in human glymphatics-on-chip models
A human glymphatics-on-chip model reveals that monomeric and oligomeric amyloid-β cause distinct Alzheimer's disease pathophysiological characteristics in astrocytes.
Lab Chip, 2024,24, 3826-3839
https://doi.org/10.1039/D4LC00287C
Multioxide combinatorial libraries: fusing synthetic approaches and additive technologies for highly orthogonal electronic noses
Liquid phase synthesis methods coupled with advanced additive techniques, and combinatorial approaches create new possibilities in the design of gas analytical systems. Particular sensor combinations enhance the performance of analyte classification.
Lab Chip, 2024,24, 3810-3825
https://doi.org/10.1039/D4LC00252K
Microfluidic finger-actuated mixer for ultrasensitive electrochemical measurements of protein biomarkers for point-of-care testing
We report a microfluidic electrochemical immunosensor that employs a unique finger-actuated mixer for rapid (<25 min), ultrasensitive (∼5 pg mL−1) measurements of protein biomarkers in human plasma using a smartphone-based diagnostic device.
Lab Chip, 2024,24, 3802-3809
https://doi.org/10.1039/D4LC00207E
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
A microfluidic co-culture model for investigating colonocytes–microbiota interactions in colorectal cancer
Changes in the abundance of certain bacterial species within the colorectal microbiota correlate with colorectal cancer (CRC) development.
Lab Chip, 2024,24, 3690-3703
https://doi.org/10.1039/D4LC00013G
Droplet drinking in constrictions
When droplets pass through constrictions, they exhibit a behavior akin to cellular pinocytosis, forming intricate multiple emulsions.
Lab Chip, 2024,24, 3412-3421
https://doi.org/10.1039/D4LC00381K
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Ultrasensitive quantification of PD-L1+ extracellular vesicles in melanoma patient plasma using a parallelized high throughput droplet digital assay
We develop a high-throughput droplet-based extracellular vesicle analysis (DEVA) assay for ultrasensitive quantification of EVs in plasma that are positive for both PD-L1 and tetraspanins.
Lab Chip, 2024,24, 3403-3411
https://doi.org/10.1039/D4LC00331D
About this collection
This themed collection features articles published in Lab on a Chip marked as HOT by the handling editor or as recommended by referees. Congratulations to all the authors whose articles are featured.