Viewpoint
Unlocking the potential of metal ligand cooperation for enantioselective transformations
Metal–ligand cooperation, (MLC) is a versatile catalysis concept. Herein, we discuss the historical context, mechanisms, and applications, suggesting exploring MLC for enantioselective transformations beyond (de)hydrogenative processes.
Review Article
Recent advances in Rh(I)-catalyzed enantioselective C–H functionalization
This review aims to provide the most comprehensive and up-to-date summary of recent advances in Rh(I)-catalyzed enantioselective C−H functionalization highlighting diverse reaction development, chiral ligand design and mechanistic investigation.
Metal-catalyzed asymmetric reactions enabled by organic peroxides
This review summarizes the advances in metal-catalyzed asymmetric reactions enabled by organic peroxides that have been found to exhibit multifunctionalities, for instance, applied as stoichiometric reactants, stoichiometric reagents, or catalytic amount reagents.
Pd-Catalysed asymmetric allylic alkylation of heterocycles: a user's guide
This review analyses recent advances and strategies employed in the Pd-AAA of nucleophilic prochiral heterocycles. Each section is focused on a specific heterocycle, where optimisation data and reaction scope have been carefully analysed.
Recent advances in Pd-catalyzed asymmetric cyclization reactions
This review aims to collect advancements in enantioselective palladium-catalyzed cyclization reactions over the past eleven years, and it is organized into thirteen sections depending on the different types of transformations involved.
Synthesis, stereochemical assignment, and enantioselective catalytic activity of late transition metal planar chiral complexes
Planer chiral complexes emerge as powerful tools for enantioselective catalysis.
Enantioconvergent transformations of secondary alcohols through borrowing hydrogen catalysis
Enantioconvergent transformations of racemic secondary alcohols to enantioenriched chiral amines, N-heterocycles, higher-order alcohols and ketones through borrowing hydrogen catalysis is covered in this review.
Review Article
Asymmetric arene hydrogenation: towards sustainability and application
This review summarises the state-of-the-art in transition-metal catalysed asymmetric hydrogenation of (hetero)arenes and highlights recent advances with a special focus on sustainability while also addressing its shortcomings.
A tutorial on asymmetric electrocatalysis
This tutorial review delves into the unique advantages of electrochemistry in the context of asymmetric catalysis, first providing a brief tutorial introduction to electrosynthesis, then exploring representative case studies with a mechanistic focus.
About this collection
Asymmetric catalysis has remained at the forefront of organic synthesis since its inception more than half a century ago. Metals, especially transition metals, played an important role in shaping this research field in its infancy. Notwithstanding the tremendous growth in other areas of asymmetric catalysis, metal catalysis continues to deliver unprecedented transformations.
This Themed Collection on Metals in Asymmetric Catalysis, Guest Edited by Steve Malcolmson (Duke University, USA), Santanu Mukherjee (Indian Institute of Science, Bangalore, India), Uttam Tambar (University of Texas Southwestern, USA) and Yong Tang (Shanghai Institute of Organic Chemistry, China), comprises of recent developments in the areas of enantioselective catalysis proceeding through the involvement of transition metal complexes.