Quantum cascade lasers (QCLs) in biomedical spectroscopy

Andreas Schwaighofer, Markus Brandstetter and Bernhard Lendl

Chem. Soc. Rev., 2017, 46, 5903
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Exploration of utility of combined optical photothermal infrared and Raman imaging for investigating the chemical composition of microcalcifications in breast cancer

Pascaline Bouzy, Iain D. Lyburn, Sarah E. Pinder, Robert Scott, Jessica Mansfield, Julian Moger, Charlene Greenwood, Ihssane Bouybayoune, Eleanor Cornford, Keith Rogers and Nick Stone

Anal. Methods, 2023, 15, 1620
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Biomedical applications of mid-infrared quantum cascade lasers – a review

Katharina Isensee, Niels Kröger-Lui and Wolfgang Petrich

Analyst, 2018, 143, 5888
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Recent advancements of EC-QCL based mid-IR transmission spectroscopy of proteins and application to analysis of bovine milk1

Andreas Schwaighofer, Mirta R. Alcaráz, Julia Kuligowski and Bernhard Lendl

BSI, 2018, 7, 35
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Mitigating fringing in discrete frequency infrared imaging using time-delayed integration

Shihao Ran, Sebastian Berisha, Rupali Mankar, Wei-Chuan Shih and David Mayerich

Biomed. Opt. Express, 2018, 9, 832
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Label-free Aβ plaque detection in Alzheimer's disease brain tissue using infrared microscopy and neural networks

Dajana Müller, Dominik Röhr, Baayla D.C. Boon, Maximilian Wulf, Thomas Arto, Jeroen J.M. Hoozemans, Katrin Marcus, Annemieke J.M. Rozemuller, Frederik Großerueschkamp, Axel Mosig and Klaus Gerwert

Heliyon, 2025, 11, e42111
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Deep learning-based protocols to enhance infrared imaging systems

Kianoush Falahkheirkhah, Kevin Yeh, Shachi Mittal, Luke Pfister and Rohit Bhargava

Chemometrics and Intelligent Laboratory Systems, 2021, 217, 104390
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Exploring Feature Selection with Deep Learning for Kidney Tissue Microarray Classification Using Infrared Spectral Imaging

Zachary Caterer, Jordan Langlois, Connor McKeown, Mikayla Hady, Samuel Stumo, Suman Setty, Michael Walsh and Rahul Gomes

Bioengineering, 2025, 12, 366
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Label-free Identification of Antibody-mediated Rejection in Cardiac Allograft Biopsies Using Infrared Spectroscopic Imaging

Imran Uraizee, Vishal K. Varma, Hari Sreedhar, Francesca Gambacorta, Shaiju S. Nazeer, Aliya Husain and Michael J. Walsh

Transplantation, 2019, 103, 698
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High-speed scanless entire bandwidth mid-infrared chemical imaging

Yue Zhao, Shota Kusama, Yuji Furutani, Wei-Hong Huang, Chih-Wei Luo and Takao Fuji

Nat Commun, 2023, 14
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Vibrational spectroscopic imaging of pathogens, microorganisms, and their interactions with host systems

Alison J. Hobro and Nicholas I. Smith

Optics Communications, 2018, 422, 75
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Quantum Cascade Laser-Based Infrared Microscopy for Label-Free and Automated Cancer Classification in Tissue Sections

Claus Kuepper, Angela Kallenbach-Thieltges, Hendrik Juette, Andrea Tannapfel, Frederik Großerueschkamp and Klaus Gerwert

Sci Rep, 2018, 8
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Statistical Considerations and Tools to Improve Histopathologic Protocols with Spectroscopic Imaging

Shachi Mittal, Jonathan Kim and Rohit Bhargava

Appl Spectrosc, 2022, 76, 428
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Spectroscopic imaging of biomaterials and biological systems with FTIR microscopy or with quantum cascade lasers

James A. Kimber and Sergei G. Kazarian

Anal Bioanal Chem, 2017, 409, 5813
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Analysis of Fixed and Live Single Cells Using Optical Photothermal Infrared with Concomitant Raman Spectroscopy

Alice Spadea, Joanna Denbigh, M. Jayne Lawrence, Mustafa Kansiz and Peter Gardner

Anal. Chem., 2021, 93, 3938
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Probing the micro- and nanoscopic properties of dental materials using infrared spectroscopy: A proof-of-principle study

Max Beddoe, Thorsten Gölz, Martin Barkey, Enrico Bau, Matthias Godejohann, Stefan A. Maier, Fritz Keilmann, Marioara Moldovan, Doina Prodan, Nicoleta Ilie and Andreas Tittl

Acta Biomaterialia, 2023, 168, 309
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Diffraction-limited hyperspectral mid-infrared single-pixel microscopy

Alexander Ebner, Paul Gattinger, Ivan Zorin, Lukas Krainer, Christian Rankl and Markus Brandstetter

Sci Rep, 2023, 13
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Infrared spectroscopic laser scanning confocal microscopy for whole-slide chemical imaging

Kevin Yeh, Ishaan Sharma, Kianoush Falahkheirkhah, Matthew P. Confer, Andres C. Orr, Yen-Ting Liu, Yamuna Phal, Ruo-Jing Ho, Manu Mehta, Ankita Bhargava, Wenyan Mei, Georgina Cheng, John C. Cheville and Rohit Bhargava

Nat Commun, 2023, 14
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Application of Vibrational Spectroscopy and Imaging to Point-of-Care Medicine: A Review

Susanne Pahlow, Karina Weber, Jürgen Popp, Bayden R. Wood, Kamila Kochan, Anja Rüther, David Perez-Guaita, Philip Heraud, Nick Stone, Alex Dudgeon, Ben Gardner, Rohith Reddy, David Mayerich and Rohit Bhargava

Appl Spectrosc, 2018, 72, 52
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Digital Histopathology by Infrared Spectroscopic Imaging

Rohit Bhargava

Annual Rev. Anal. Chem., 2023, 16, 205
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Mid-IR hyperspectral imaging for label-free histopathology and cytology

M Hermes, R Brandstrup Morrish, L Huot, L Meng, S Junaid, J Tomko, G R Lloyd, W T Masselink, P Tidemand-Lichtenberg, C Pedersen, F Palombo and N Stone

J. Opt., 2018, 20, 023002
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Mid-infrared hyperspectral single-pixel microscopy with a quantum cascade laser

Augustin Zuljevic, Alexander Ebner, Paul Gattinger, Ivan Zorin, Christian Rankl, Kurt Hingerl and Markus Brandstetter

Opt. Express, 2024, 32, 35184
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Influence of denoising on classification results in the context of hyperspectral data: High Definition FT-IR imaging

Magda K. Raczkowska, Paulina Koziol, Slawka Urbaniak-Wasik, Czeslawa Paluszkiewicz, Wojciech M. Kwiatek and Tomasz P. Wrobel

Analytica Chimica Acta, 2019, 1085, 39
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Quantum Cascade Laser-Based Infrared Imaging as a Label-Free and Automated Approach to Determine Mutations in Lung Adenocarcinoma

Nina Goertzen, Roberto Pappesch, Jana Fassunke, Thomas Brüning, Yon-Dschun Ko, Joachim Schmidt, Frederik Großerueschkamp, Reinhard Buettner and Klaus Gerwert

The American Journal of Pathology, 2021, 191, 1269
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Portable Spectroscopy

Richard A. Crocombe

Appl Spectrosc, 2018, 72, 1701
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Biochemical detection of fatal hypothermia and hyperthermia in affected rat hypothalamus tissues by Fourier transform infrared spectroscopy

Hancheng Lin, Kaifei Deng, Ji Zhang, Lei Wang, Zhong Zhang, Yiwen Luo, Qiran Sun, Zhengdong Li, Yijiu Chen, Zhenyuan Wang and Ping Huang

Bioscience Reports, 2019, 39
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Rapid intraoperative diagnosis of gynecological cancer by ATR‐FTIR spectroscopy of fresh tissue biopsy

Dov Malonek, Ben‐Zion Dekel, Gabi Haran, Renat Reens‐Carmel, Gabriel M. Groisman, Mordechai Hallak and Ilan Bruchim

Journal of Biophotonics, 2020, 13
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Microbial Identification Through Multispectral Infrared Imaging of Colonies: A New Type of Morpho‐Spectral Fingerprinting

Joel Le Galudec, Mathieu Dupoy, Laurent Duraffourg, Véronique Rebuffel and Pierre R. Marcoux

Microbial Biotechnology, 2025, 18
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