Issue 26, 2016

Surface-enhanced Raman spectroscopy on porous silicon membranes decorated with Ag nanoparticles integrated in elastomeric microfluidic chips

Abstract

A microfluidic sensing device is fabricated by the integration of silver-coated porous silicon membranes as surface enhanced Raman scattering active nanostructures in a PDMS matrix showing plasmon resonances in the visible energy range. The membranes are shaped by defining a suitable pattern of the electrochemically etched silicon using the cover of the elastomeric chip. 4-Mercaptobenzoic acid, used as a probe molecule, shows Raman enhancement larger than 107 in electronic off-resonance conditions. The calibration of the SERS substrate is performed using a Langmuir isotherm fit, evidencing the analyte chemisorption. In order to check the potential of the chip as a multiplexed biosensing platform, model oligonucleotides (polyadenine, polyguanine, polythymine and polycytosine) are analyzed in a multichamber system.

Graphical abstract: Surface-enhanced Raman spectroscopy on porous silicon membranes decorated with Ag nanoparticles integrated in elastomeric microfluidic chips

Supplementary files

Article information

Article type
Paper
Submitted
14 ဒီ 2015
Accepted
10 ဖေ 2016
First published
12 ဖေ 2016

RSC Adv., 2016,6, 21865-21870

Surface-enhanced Raman spectroscopy on porous silicon membranes decorated with Ag nanoparticles integrated in elastomeric microfluidic chips

C. Novara, A. Lamberti, A. Chiadò, A. Virga, P. Rivolo, F. Geobaldo and F. Giorgis, RSC Adv., 2016, 6, 21865 DOI: 10.1039/C5RA26746C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements