Catalytic fluorination of unactivated C(sp3)–H bonds

Abstract

Organofluorine compounds have found widespread applications in the pharmaceutical and agrochemical industries. Efficient construction of organofluorine molecules is highly desirable. Catalytic transformation of C(sp³)–H bonds into C(sp³)–F bonds provides the simplest and most straightforward way to organofluorine compounds. This Highlight discusses the most recent findings in the field.