Issue 38, 2009
From the journal:

Chemical Communications

β-Amidoaldehydes viaoxazolinehydroformylation†‡

David S. Laitar,a   John W. Kramer,a   Bryan T. Whiting,a   Emil B. Lobkovskya  and  Geoffrey W. Coates*a  

* Corresponding authors

a Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, USA
E-mail: gc39@cornell.edu
Fax: +1 607-255-4137
Tel: +1 607-255-5447

Abstract

4-Substituted oxazolines, which are readily synthesized from naturally occurring α-amino acids, are converted efficiently and stereospecifically to β-amidoaldehydes in the presence of synthesis gas and catalytic dicobalt octacarbonyl.

Graphical abstract: β-Amidoaldehydes viaoxazolinehydroformylation

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Article information

DOI
https://doi.org/10.1039/B913698C
Article type
Communication
Submitted
09 ဇူ 2009
Accepted
10 ဩ 2009
First published
01 စက် 2009

Chem. Commun., 2009, 5704-5706

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β-Amidoaldehydes viaoxazolinehydroformylation

D. S. Laitar, J. W. Kramer, B. T. Whiting, E. B. Lobkovsky and G. W. Coates, Chem. Commun., 2009, 5704 DOI: 10.1039/B913698C

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