Ligand-ligated Ni–Al bimetallic catalysis for C–H and C–C bond activation

Abstract

Compared with non-ligated Ni–Al bimetallic catalysis, bifunctional ligand-ligated Ni–Al bimetallic catalysis displays stronger synergism, not only affecting the electronic properties and steric hindrance of substrates, but also producing a directing effect for facile control of reactivity, site selectivity and enantioselectivity in the activation of C–H and C–C bonds. This review will give a brief summary of research advances in this field, highlighting the development of bifunctional ligands and their applications.