Issue 42, 2018

Rhodium at the chemistry–biology interface

Abstract

As a rare element with no known natural biological function, rhodium has a limited history in biological chemistry and chemical biology. However, rhodium complexes have unique structure and reactivity attributes, and chemists have increasingly used these attributes to probe and perturb living systems. This brief review focuses on recent advances in the use of rhodium complexes in biological contexts, including medicinal chemistry, protein science, and chemical biology. In particular, we highlight both structure- and reactivity-driven approaches to biological probes and discuss how coordination environment affects molecular properties in a biological environment.

Graphical abstract: Rhodium at the chemistry–biology interface

Article information

Article type
Frontier
Submitted
24 ဇူ 2018
Accepted
13 စက် 2018
First published
14 စက် 2018

Dalton Trans., 2018,47, 14855-14860

Author version available

Rhodium at the chemistry–biology interface

J. Ohata and Z. T. Ball, Dalton Trans., 2018, 47, 14855 DOI: 10.1039/C8DT03032D

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