Issue 20, 2016
From the journal:

Journal of Materials Chemistry B

Low molecular weight gels induced differentiation of mesenchymal stem cells†

Yalong Hu,a   Wenxia Gao,*a   Fang Wu,b   Huayue Wu,a   Bin Heb  and  Jing He*b  

* Corresponding authors

a College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325027, China
E-mail: wenxiag@wzu.edu.cn

b National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China
E-mail: jinghe30@scu.edu.cn

Abstract

Four low molecular weight gels (LMWGs) with different moduli were fabricated as scaffolds to investigate the differentiation of mesenchymal stem cells (MSCs). The MSCs differentiated to osteoblasts in rigid LMWGs and to chondrocytes in soft LMWGs. The critical modulus to induce the different differentiations was between 10 and 20 kPa.

Graphical abstract: Low molecular weight gels induced differentiation of mesenchymal stem cells

  • This article is part of the themed collection: Stem Cells
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Article information

DOI
https://doi.org/10.1039/C5TB02546J
Article type
Communication
Submitted
03 ဒီ 2015
Accepted
15 ဖေ 2016
First published
16 ဖေ 2016

J. Mater. Chem. B, 2016,4, 3504-3508

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Low molecular weight gels induced differentiation of mesenchymal stem cells

Y. Hu, W. Gao, F. Wu, H. Wu, B. He and J. He, J. Mater. Chem. B, 2016, 4, 3504 DOI: 10.1039/C5TB02546J

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