Issue 4, 2016
From the journal:

Organic Chemistry Frontiers

Synthesis of fused isoquinolines via gold-catalyzed tandem alkyne amination/intramolecular O–H insertion†

Yuan Pan,a   Gui-Wei Chen,b   Cang-Hai Shen,b   Weimin He*a  and  Long-Wu Ye*bc  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China

b State Key Laboratory of Physical Chemistry of Solid Surfaces & The Key Laboratory for Chemical Biology of Fujian Province, Department of Chemistry, Xiamen University, Xiamen 361005, China
E-mail: longwuye@xmu.edu.cn

c State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

Abstract

A novel gold-catalyzed tandem alkyne amination/intramolecular O–H insertion has been developed. A variety of [1,4]oxazino[3,2-c]isoquinolines are readily accessed under mild reaction conditions by utilizing this strategy, thereby providing an efficient and practical route for the construction of synthetically useful fused isoquinolines.

Graphical abstract: Synthesis of fused isoquinolines via gold-catalyzed tandem alkyne amination/intramolecular O–H insertion

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6QO00033A
Article type
Research Article
Submitted
20 ဇန် 2016
Accepted
12 ဖေ 2016
First published
12 ဖေ 2016

Org. Chem. Front., 2016,3, 491-495

Permissions

Request permissions

Synthesis of fused isoquinolines via gold-catalyzed tandem alkyne amination/intramolecular O–H insertion

Y. Pan, G. Chen, C. Shen, W. He and L. Ye, Org. Chem. Front., 2016, 3, 491 DOI: 10.1039/C6QO00033A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements