Issue 9, 2015
From the journal:

Chemical Communications

Compact multi-enzyme pathways in P. pastoris†

Martina Geier,‡a   Pia Fauland,‡a   Thomas Voglb  and  Anton Glieder*b  

* Corresponding authors

a Austrian Centre of Industrial Biotechnology (ACIB GmbH), Petersgasse 14, 8010 Graz, Austria

b Institute of Molecular Biotechnology, NAWI Graz & DK Molecular Enzymology, TU Graz, Petersgasse 14, 8010 Graz, Austria
E-mail: anton.glieder@tugraz.at

Abstract

We report for the first time the functional simultaneous expression of nine genes from a single 2A peptide based polycistronic expression construct. The feasibility and arising opportunities for the biosynthetic pathway balancing for chemical production were demonstrated by the co-expression of the violacein and carotenoid biosynthesis pathways.

Graphical abstract: Compact multi-enzyme pathways in P. pastoris

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4CC08502G
Article type
Communication
Submitted
28 အောက် 2014
Accepted
03 ဒီ 2014
First published
03 ဒီ 2014
This article is Open Access
Creative Commons BY license

Chem. Commun., 2015,51, 1643-1646

Author version available

Download author version (PDF)

Permissions

Request permissions

Compact multi-enzyme pathways in P. pastoris

M. Geier, P. Fauland, T. Vogl and A. Glieder, Chem. Commun., 2015, 51, 1643 DOI: 10.1039/C4CC08502G

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements