Issue 43, 2023

A new method for rapid identification of traditional Chinese medicine based on a new silver sol: using the SERS spectrum for quality control of flavonoids and flavonoid glycosides in Potentilla discolor Bge.

Abstract

Rapid identification of the structure and active components of traditional Chinese medicine is still limited due to low extraction efficiency, long time requirements and imprecision. To overcome these limitations, we developed a novel surface-enhanced Raman spectroscopy (SERS) base, Ag@Cs nanoparticles, which enhanced the effectiveness of Raman spectroscopy and enabled trace analysis of drugs. Cesium ions have remarkable chemical activity and photoelectric effects. Here, the novel approach involved using cesium ions as focusing agents and thiosulfate ions as cleaning agents. Its distinctive feature lies in the introduction of cesium ions as focusing agents, which facilitates the surface modification of silver nanoparticles, leading to the formation of hotspots and consequently achieving highly repetitive and high signal-to-noise ratio Raman spectra. The results demonstrated that Ag@Cs, compared with the original method, greatly enhanced the spectral signal magnitude of glycogens and glycosides in twenty kinds of Potentilla discolor Bge. Additionally, Ag@Cs SERS enabled the analysis of glycogens and glycosides in twenty samples, which showed obvious and different corresponding characteristic peaks to distinguish them. Furthermore, by analyzing the peak spectrum information and principal component analysis of glycogen and glycoside components from ten different origins, the quality of the different origins can be determined. Compared with the original method, it was proved that Ag@Cs base could overcome the influence of citrate ions and was effectively applied in the SERS detection of flavonoids containing fluorescent components. Therefore, this method has potential applications in Chinese medicine quality control and testing technology.

Graphical abstract: A new method for rapid identification of traditional Chinese medicine based on a new silver sol: using the SERS spectrum for quality control of flavonoids and flavonoid glycosides in Potentilla discolor Bge.

  • This article is part of the themed collection: #MyFirstJMCC

Supplementary files

Article information

Article type
Paper
Submitted
03 ဩ 2023
Accepted
12 စက် 2023
First published
13 စက် 2023

J. Mater. Chem. C, 2023,11, 15138-15148

A new method for rapid identification of traditional Chinese medicine based on a new silver sol: using the SERS spectrum for quality control of flavonoids and flavonoid glycosides in Potentilla discolor Bge.

M. Du, Z. Sun, M. Xie, S. Gu, Y. Chen and Q. Wang, J. Mater. Chem. C, 2023, 11, 15138 DOI: 10.1039/D3TC02768F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements