Issue 27, 2019

Characterization of the structural, optical, photocatalytic and in vitro and in vivo anti-inflammatory properties of Mn2+ doped Zn2GeO4 nanorods

Abstract

The effect of Mn incorporation on the structural, optical, and photocatalytic properties of Zn2GeO4 (ZGO) host matrices was investigated. Moreover, the ability to modulate in vitro inflammatory mediators and in vivo acute inflammation of Mn-doped ZGO (ZGO:Mn) was evaluated for the first time. We used a one-pot hydrothermal approach for preparing shape-controlled ZGO nanorods with 0, 1, 2, and 4% Mn2+ (ZGO:Mn). Both the ZGO and ZGO:Mn nanorods showed a rhombohedral structure and excellent optical properties with photoluminescence (PL) emission in the visible region at 543 nm attributed to the electronic transitions (4T16A1) among the 3d5 orbitals of the incorporated Mn2+ ions in [MnO4] clusters. The nanorods were found to be efficient photocatalysts for the ultraviolet degradation of methylene blue in the presence of H2O2. The ZGO:Mn nanorod catalyst with 2% Mn showed the best methylene blue degradation (complete degradation within 10 min). The surface acidity of the ZGO:Mn nanorods also contributed to their photocatalytic ability. Meanwhile, the ZGO:Mn nanorods significantly reduced the tumor necrosis factor and nitric oxide content. Hence, the 4%-doped nanorods were found to be highly effective in the reduction of carrageenan-induced paw edema. The acute inflammation (on macrophages) results revealed that the nanorods with 4% Mn2+ exhibited promising anti-inflammatory properties.

Graphical abstract: Characterization of the structural, optical, photocatalytic and in vitro and in vivo anti-inflammatory properties of Mn2+ doped Zn2GeO4 nanorods

Article information

Article type
Paper
Submitted
02 မတ် 2019
Accepted
14 မေ 2019
First published
14 မေ 2019

J. Mater. Chem. C, 2019,7, 8216-8225

Characterization of the structural, optical, photocatalytic and in vitro and in vivo anti-inflammatory properties of Mn2+ doped Zn2GeO4 nanorods

V. Y. Suzuki, L. H. C. Amorin, N. M. Lima, E. G. Machado, P. E. Carvalho, S. B. R. Castro, C. C. S. Alves, A. P. Carli, M. S. Li, E. Longo and F. A. La Porta, J. Mater. Chem. C, 2019, 7, 8216 DOI: 10.1039/C9TC01189G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements