Issue 39, 2019

Facile access to evodiakine enabled by aerobic copper-catalyzed oxidative rearrangement

Abstract

Oxidation as a fundamentally important method for the synthesis of complex structures is difficult to achieve in a selective manner. Evodiakine, a complex natural product possessing an unprecedented ring system (6/5/5/7/6), has a high oxidation state without a practical solution. Herein, we report the first synthesis of evodiakine via aerobic copper-catalyzed late-stage functionalization of evodiamine.

Graphical abstract: Facile access to evodiakine enabled by aerobic copper-catalyzed oxidative rearrangement

Supplementary files

Article information

Article type
Communication
Submitted
20 ဩ 2019
Accepted
24 စက် 2019
First published
25 စက် 2019

Org. Biomol. Chem., 2019,17, 8811-8815

Facile access to evodiakine enabled by aerobic copper-catalyzed oxidative rearrangement

Y. Su, G. Huang, F. Ye, P. Qiao, J. Ye, Y. Gao and H. Chen, Org. Biomol. Chem., 2019, 17, 8811 DOI: 10.1039/C9OB01832H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements