From the journal:

Chemical Communications

Red-Light Excitation of a Ru(II)-Pt(II) Tetranuclear Complex for Combined Photoactivated Chemotherapy and Photodynamic Therapy

Pia Siekierski,   Eleni Michaltsis,   Julia Schleisiek,   Nicolás Montesdeoca  and  Johannes Karges  

Abstract

We report the synthesis and biological evaluation of a tetranuclear Ru(II)-Pt(II) complex activated by red light (630 nm). Upon irradiation, the Ru(II) center photo-catalytically generates singlet oxygen while simultaneously releasing Pt(II) moieties, thereby inducing a multimodal therapeutic effect in cancer cells by photodynamic therapy and photoactivated chemotherapy.

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D5CC05177K
Article type
Communication
Submitted
08 Sep 2025
Accepted
07 Oct 2025
First published
07 Oct 2025
This article is Open Access
Creative Commons BY license

Chem. Commun., 2025, Accepted Manuscript

Permissions

Request permissions

Red-Light Excitation of a Ru(II)-Pt(II) Tetranuclear Complex for Combined Photoactivated Chemotherapy and Photodynamic Therapy

P. Siekierski, E. Michaltsis, J. Schleisiek, N. Montesdeoca and J. Karges, Chem. Commun., 2025, Accepted Manuscript , DOI: 10.1039/D5CC05177K

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements