Issue 14, 2014

A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells

Abstract

A novel near-infrared (NIR) and colorimetric fluorescent molecular probe based on a dicyanomethylene-4H-pyran chromophore for the selective detection of glutathione in living cells has been developed. The fluorescence OFF–ON switch is triggered by cleavage of the 2,4-dinitrobenzensulfonyl (DNBS) unit by the interaction with GSH.

Graphical abstract: A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells

Supplementary files

Article information

Article type
Communication
Submitted
23 окт. 2013
Accepted
03 дек. 2013
First published
04 дек. 2013
This article is Open Access
Creative Commons BY license

Chem. Commun., 2014,50, 1751-1753

A near-infrared colorimetric fluorescent chemodosimeter for the detection of glutathione in living cells

M. Li, X. Wu, Y. Wang, Y. Li, W. Zhu and T. D. James, Chem. Commun., 2014, 50, 1751 DOI: 10.1039/C3CC48128J

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