Issue 26, 2009
From the journal:

Chemical Communications

Rhodium catalyzed enantioselective cyclization of substituted imidazolesvia C–H bond activation†‡

Andy S. Tsai,b   Rebecca M. Wilson,b   Hitoshi Harada,b   Robert G. Bergman*a  and  Jonathan A. Ellman*b  

* Corresponding authors

a Division of Chemical Sciences, Lawrence Berkeley National Laboratory and Department of Chemistry, University of California, Berkeley, USA
E-mail: rbergman@berkeley.edu
Fax: +1 510 642 7714
Tel: +1 510 642 2156

b Department of Chemistry, University of California, Berkeley, USA
E-mail: jellman@berkeley.edu
Fax: +1 510 666 2504
Tel: +1 510 642 4488

Abstract

The enantioselective intramolecular alkylation of substituted imidazoles with enantiomeric excesses up to 98% has been accomplished by rhodium catalyzed C–H bond functionalization with (S,S′,R,R′)TangPhos as the chiral ligand.

Graphical abstract: Rhodium catalyzed enantioselective cyclization of substituted imidazoles via C–H bond activation

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B902878A
Article type
Communication
Submitted
11 фев. 2009
Accepted
01 мај 2009
First published
02 јун. 2009

Chem. Commun., 2009, 3910-3912

Permissions

Request permissions

Rhodium catalyzed enantioselective cyclization of substituted imidazoles via C–H bond activation

A. S. Tsai, R. M. Wilson, H. Harada, R. G. Bergman and J. A. Ellman, Chem. Commun., 2009, 3910 DOI: 10.1039/B902878A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements