Issue 33, 2024

Application of a calcium and phosphorus biomineralization strategy in tooth repair: a systematic review

Abstract

Biomineralization is a natural process in which organisms regulate the growth of inorganic minerals to form biominerals with unique layered structures, such as bones and teeth, primarily composed of calcium and phosphorus. Tooth decay significantly impacts our daily lives, and the key to tooth regeneration lies in restoring teeth through biomimetic approaches, utilizing mineralization strategies or materials that mimic natural processes. This review delves into the types, properties, and transformations of calcium and phosphorus minerals, followed by an exploration of the mechanisms behind physiological and pathological mineralization in living organisms. It summarizes the mechanisms and commonalities of biomineralization and discusses the advancements in dental biomineralization research, guided by insights into calcium and phosphorus mineral biomineralization. This review concludes by addressing the current challenges and future directions in the field of dental biomimetic mineralization.

Graphical abstract: Application of a calcium and phosphorus biomineralization strategy in tooth repair: a systematic review

Article information

Article type
Review Article
Submitted
22 апр. 2024
Accepted
10 јул. 2024
First published
12 јул. 2024

J. Mater. Chem. B, 2024,12, 8033-8047

Application of a calcium and phosphorus biomineralization strategy in tooth repair: a systematic review

H. Dong, D. Wang, H. Deng, L. Yin, X. Wang, W. Yang and K. Cai, J. Mater. Chem. B, 2024, 12, 8033 DOI: 10.1039/D4TB00867G

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