Mechanistic Advances in Hypoglycemic Effects of Natural Polysaccharides: Multi-Target Regulation of Glycometabolism and Gut Microbiota Crosstalk

Liquan Zhou, Jiani Li, Chen Ding, Yimiao Zhou and Zuowei Xiao

Molecules, 2025, 30, 1980
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Antioxidant and Hypoglycemic Activity of Polysaccharides With Different Tissues From Rosa roxburghii f. eseiosa Ku

Zhi‐Wen Wan, Rui Meng, Hua‐Yuan Yang, Xing Yang, Qin Zhou, Min Wu, Bin Li and Xia Zhang

Chemistry & Biodiversity, 2026, 23
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Bibliometric analysis of advances in polysaccharide pharmacology research: A review

Jiameng Yang, Siyuan Lei, Yanhong Wei, Yaoxuan Li, Rutong Wang, Haoxuan Xue, Qiumei Huang, Kongwei Huang and Xiaocan Lei

International Journal of Biological Macromolecules, 2025, 313, 144159
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The structure-activity relationship of polysaccharides in fruits and vegetables and interaction between polysaccharides and anthocyanins/proteins: A review

Hongkun Xue, Beimeng Liang, Lihong Ji, Xinxin Li, Miaomiao Wang, Xiaojun Liao and Jiaqi Tan

Food Research International, 2025, 211, 116371
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Structural Characterization, Constipation-Relieving, and Hypolipidemic Activity of Polysaccharides from Fresh and Processed Dendrobium officinale

Tingting Ding, Qingquan Ma, Xin Xu, Caiyue Chen, Ya Song, Xiang Zou, Shuqi Gao, Tingting Zhang, Fengzhong Wang, Jing Sun and Bei Fan

Foods, 2026, 15, 727
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Effect of bioactive Rosa roxburghii Tratt fruit polysaccharide on the structure and emulsifying property of lactoferrin protein

Wang Pingping, Du Yutong, Chai Xianghua, Chen Chun, Wu Kegang and Fu Xiong

International Journal of Biological Macromolecules, 2025, 298, 140016
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Extraction, purification, structural characterization, and bioactivities of Radix Aconiti Lateralis Preparata (Fuzi) polysaccharides: A review

Shan Zhang, Shanshan Nie, Ruipeng Wu, Xinju Chen and Peng Huang

International Journal of Biological Macromolecules, 2025, 292, 139285
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Plant Heteropolysaccharides as Potential Anti-Diabetic Agents: A Review

Dan He and Can Cui

CIMB, 2025, 47, 533
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Extraction and Structural Characterization of Four Grape Polysaccharides and Their Protective Effects in Alcohol-Induced Gastric Mucosal Injury

Jian Shao, Jizhen Li, Yonghui Zhao, Rong Huang, Aixin Guo, Lijuan Hou, Xiangpeng Leng and Qiu Li

Foods, 2024, 13, 3500
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Function of molecular-weight-optimized Astragalus polysaccharides in cisplatin-caused acute kidney injury: mechanisms centered on gut microbiota regulation and precise treatment approaches

Huijing Li, Huiqiong Li, Rongjing Wu and Miao Zhong

Front. Microbiol., 2026, 17
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Structure-activity relationships and mechanisms of natural polysaccharides in modulating neurological disorders via the microbiota-gut-brain axis

Yulin Song, Qingfang Deng, Jiawen Li, Ruhai Chen, Dan Li, Shenglin Wang, Baitong Jing and Xin Zhou

Carbohydrate Polymers, 2025, 367, 123960
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Structural characterization of β-glucan in Hericium erinaceus pretreated by steam explosion and its effects on human gut microbiota in vitro

Shuang Chen, Bingqing Ling, Xiaoyu Liu, Liping Liu, Jie Feng, Jingsong Zhang, Yan Yang, Di Wu, Qingbin Guo and Yanfang Liu

Food Chemistry, 2025, 482, 144156
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Potential prebiotic effects of tamarind seed polysaccharide: comparative evaluation of native versus enzymatic hydrolysates on the restoration of intestinal microbiota in clindamycin‐treated mice

Xianbao Sun, Xujiao Li, Yinan Chen, Lihua Song, Chunmei Yuan, Zibo Song and Yan Wu

J Sci Food Agric, 2026, 106, 3385
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In vitro digestion and fermentation of ginseng pectic polysaccharide GPS-1 and attenuation of its product on oleic acid-induced oxidative stress in HepG2 cells

Xiwen Sun, Li Liu, Wenbo Jiao, Ting Ren, Ran Zhao, Zirui Tan, Ziye Jiang, Jing Wang, Bo Li, Xiaoyu Zhang and Lili Jiao

Front. Pharmacol., 2026, 17
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Preparation, characterization and anti-fatigue activity of polysaccharides from Pleurotus eryngii

Jianrui Sun, Linlin Yao, Ruirui Ren, Li Tong, Jiaqi Fan, Shanshan Tie, Dahong Wang and Shaobin Gu

Food Sci Biotechnol, 2026, 35, 1919
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A review: hepatoprotective compounds and its mechanism of medicine-food homology resources

Qingtao Hu, Shuangshuang Zhang, Junshang Liu, Yali Liu, Xiaoyu Chen and Jinmei Wang

Agric. Prod. Process. Sto., 2025, 1
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A review on molecular crosstalk: Bioactive polysaccharides and gut microbiota in type 2 diabetes—Pathways, signaling, and therapeutic translation

Muhsin Ali, Li Shen, Siyue Lou and Yongmin Zhang

International Journal of Biological Macromolecules, 2026, 355, 151459
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An ultrasonic degraded polysaccharide extracted from Pueraria lobata ameliorate ischemic brain injury in mice by regulating the gut microbiota and LPS-TLR4 pathway

Yulong Zhang, Zuman Dou, Shanshan Li, Huaying Zhang, Shanshui Zeng, Xiangyu Zuo, Yu Xiao, Lingling Zhang, Zhixin Li, Qingfeng Zhu, Wenyang Zhang, Hui Niu, Qingfei Duan, Xiaoxia Chen, Zhuang Li, Hongwei Zhou and Qian Wang

Ultrasonics Sonochemistry, 2025, 112, 107200
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Structural characteristics of neutral polysaccharides purified from coix seed and its anti‐insulin resistance effects on HepG2 cells

Guozhen Wu, Shuang Liu, Zhenqiang Wang and Xiao Wang

Food Science & Nutrition, 2024, 12, 8419
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Achyranthes bidentata polysaccharides alleviates rheumatoid arthritis via the gut microbiota-barrier-metabolite axis in vitro and in vivo

Dongdong Guo, Wenlida Mu, Fanglin Shen, Yu Liu, Chang Liu and He Qian

International Journal of Biological Macromolecules, 2026, 340, 149469
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Digestive properties in fermentation driven interactions of plant polysaccharides with gut microbiota and their health implications

Ziye Jiang, Bo Li, Ran Zhao, Xuyan Zhao, Xiaoyu Zhang and Lili Jiao

Front. Pharmacol., 2026, 17
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Raspberry polysaccharide extraction, purification, structural characterization, and biological activity research progress: A review

Fangyao Zhao, Junhao Li, Jian Yang and Ke Yang

International Journal of Biological Macromolecules, 2026, 335, 149278
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Ultrasound-induced modifications of Auricularia auricula polysaccharides: Implications for antioxidant and glucose-lowering activities

Te Yu, Yonggang Dai, Zifei Wang, Yang Gao and Qiong Wu

Food Chemistry: X, 2025, 25, 102209
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Systematic analysis of the potential prebiotic effects of Blackberry Seed Polysaccharides by utilizing the in vitro spatio-temporal dynamic digestion models

Chenyang Liu, Yuchi Zhou, Weirong Feng, Yuying Wang, Xiaobei Zhan, Yun Jiang, Xiaonan Zhu, Qingyu Wang, Qijun Pan, Liping Xu, Jun Kang, Guoan Zhu, Houjun Xu, Minjie Gao and Zhitao Li

Food Research International, 2025, 221, 117315
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Ideal dietary fiber model: Personalized gut microbiota modulation based on structure-function relationships

Chengming Wang, Shining Qin, Jiaqi Shi, Junrui Zhu, Xiaoxue Ju, Wenjing Wang and Lijie Yang

Carbohydrate Polymers, 2025, 368, 124097
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Recent developments in mulberry (Morus alba L.) fruit polysaccharides: isolation, purification, structural characteristics, biological activities, and applications

Siqi Liu, Hong Zhao and Xiaoliang Li

Food Hydrocolloids, 2026, 173, 112253
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Therapeutic potential of polysaccharides in type 2 diabetes mellitus via multi-target modulation of gut microbiota

Xiaolong Shang, Guangdong Hu, Mingrui Zhang, Jin Zuo, Mengyan Wang, Jiangping Wu, Qiuyue Lv, Yuyan Zhou, Taili Shao and Guodong Wang

Chinese Herbal Medicines, 2025
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Ultrasound-microwave-enzyme synergistic extraction of Brassica rapa L. polysaccharides: Structural characterization, in vitro fecal fermentation dynamics, and gut microbiota modulation

Dongdong Guo, Jiayu Lei, Hongkang Zhu, Wenlida Mu, Yuliang Cheng, Yahui Guo, Weirong Yao, Chang Liu and He Qian

International Journal of Biological Macromolecules, 2025, 327, 147493
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Enzymatic Hydrolysis of Polysaccharide from Houttuynia cordata and Structure Characterization of the Degradation Products and Their α-Glucosidase Inhibitory Activity

Lanlan Zhang, Zhixuan Yang, Yanan Yuan, Mohammed Mansour, Ting Wu, Siyi Pan and Xiaoyun Xu

Applied Sciences, 2025, 15, 11057
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Effects of extraction and modifications on physicochemical characteristics and bioactivities of lemon (Citrus limon L.) polysaccharides

Wenjing Wu, Ruizhan Chen, Ming Gao, Yan Cai, Helong Bai, Cui Yang, Dongxue Li, Yongtang Wang and Mingze Gong

Food Bioscience, 2025, 65, 105943
DOI: 10.1016/j.fbio.2025.105943

Bioactive Compounds and the Performance of Proteins as Wall Materials for Their Encapsulation

Therys Senna de Castro Oliveira, Jhonathan Valente Ferreira Gusmão, Thaís Caroline Buttow Rigolon, Daiana Wischral, Pedro Henrique Campelo, Evandro Martins and Paulo Cesar Stringheta

Micro, 2025, 5, 36
DOI: 10.3390/micro5030036

Extraction, purification, structural characteristics and biological properties of the polysaccharides from Rubus L: A review

Yihan Guo, Wenpin Qin, Yuxuan Hou, Weiwei Zhu, Haoyan Zhao, Xiaokang Zhang and Kai Jiao

Food Chemistry, 2025, 478, 143711
DOI: 10.1016/j.foodchem.2025.143711